ID A0A257GJR4_9RHOB Unreviewed; 344 AA.
AC A0A257GJR4;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Cobalamin biosynthesis protein CobW {ECO:0000313|EMBL:OYU38271.1};
GN Name=cobW {ECO:0000313|EMBL:OYU38271.1};
GN ORFNames=CFE33_17040 {ECO:0000313|EMBL:OYU38271.1};
OS Pseudorhodobacter sp. PARRP1.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Pseudorhodobacter.
OX NCBI_TaxID=2015560 {ECO:0000313|EMBL:OYU38271.1, ECO:0000313|Proteomes:UP000215760};
RN [1] {ECO:0000313|EMBL:OYU38271.1, ECO:0000313|Proteomes:UP000215760}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PARRP1 {ECO:0000313|EMBL:OYU38271.1};
RA Kojadinovic M., Villain A., Puppo C., Fon Sing S., Prioretti L., Hubert P.,
RA Gregori G., Zhang Y., Sassi J.-F., Claverie J.-M., Blanc G., Gontero B.;
RT "A metagenomic investigation of the 'star' freshwater diatom Asterionella
RT formosa and its bacterial cohort.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYU38271.1}.
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DR EMBL; NKIU01000008; OYU38271.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A257GJR4; -.
DR Proteomes; UP000215760; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0009236; P:cobalamin biosynthetic process; IEA:InterPro.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR012824; CobW.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR02475; CobW; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR PANTHER; PTHR13748:SF70; PROTEIN COBW; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000215760}.
FT DOMAIN 8..196
FT /note="CobW/HypB/UreG nucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF02492"
FT DOMAIN 254..342
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07683"
SQ SEQUENCE 344 AA; 36723 MW; 28DABA5D5C3E9C2C CRC64;
MSDLSKIPVT VITGFLGAGK TTLIRHLMQN PQGKRLAILV NEFGTVGVDG DILKSCADDN
CPVENIVELA NGCICCTVAD DFIPTIEALM ALPVRPDHII IETSGLALPK PLLKAFDWPA
IRSKITVDGV IALADAEAVA AGRFAPNVEA VDAQRMADPS LDHETPLSEV FEDQIACADI
ILMSKADLAG EAGLAAARAV ITAESPRPIP ILSMAEGIID PALILGLNAR AEDDLAARPS
HHDGHDDHEH DDFDTVVIDL PEISDIDALV ASIQRLAEEQ HILRVKGYVA VTGKPMRLLV
QAVGARVRHQ FDRPWGASPR QGQLVVIAEH HDIDLAAIRS VLGA
//
