ID A0A257GVS9_9BURK Unreviewed; 399 AA.
AC A0A257GVS9;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00012417};
DE EC=2.7.7.7 {ECO:0000256|ARBA:ARBA00012417};
DE Flags: Fragment;
GN ORFNames=CFE44_23515 {ECO:0000313|EMBL:OYU42523.1};
OS Burkholderiales bacterium PBB4.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales.
OX NCBI_TaxID=2015566 {ECO:0000313|EMBL:OYU42523.1, ECO:0000313|Proteomes:UP000216392};
RN [1] {ECO:0000313|EMBL:OYU42523.1, ECO:0000313|Proteomes:UP000216392}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PBB4 {ECO:0000313|EMBL:OYU42523.1};
RA Kojadinovic M., Villain A., Puppo C., Fon Sing S., Prioretti L., Hubert P.,
RA Gregori G., Zhang Y., Sassi J.-F., Claverie J.-M., Blanc G., Gontero B.;
RT "A metagenomic investigation of the 'star' freshwater diatom Asterionella
RT formosa and its bacterial cohort.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) =
CC diphosphate + DNA(n+1); Xref=Rhea:RHEA:22508, Rhea:RHEA-COMP:17339,
CC Rhea:RHEA-COMP:17340, ChEBI:CHEBI:33019, ChEBI:CHEBI:61560,
CC ChEBI:CHEBI:173112; EC=2.7.7.7;
CC Evidence={ECO:0000256|ARBA:ARBA00024632};
CC -!- SIMILARITY: Belongs to the DNA polymerase type-B family.
CC {ECO:0000256|ARBA:ARBA00005755}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYU42523.1}.
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DR EMBL; NKIJ01001050; OYU42523.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A257GVS9; -.
DR Proteomes; UP000216392; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR CDD; cd05537; POLBc_Pol_II; 1.
DR Gene3D; 1.10.132.60; DNA polymerase family B, C-terminal domain; 1.
DR Gene3D; 3.90.1600.10; Palm domain of DNA polymerase; 2.
DR InterPro; IPR006172; DNA-dir_DNA_pol_B.
DR InterPro; IPR017964; DNA-dir_DNA_pol_B_CS.
DR InterPro; IPR006134; DNA-dir_DNA_pol_B_multi_dom.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR042087; DNA_pol_B_thumb.
DR InterPro; IPR023211; DNA_pol_palm_dom_sf.
DR PANTHER; PTHR10322; DNA POLYMERASE CATALYTIC SUBUNIT; 1.
DR PANTHER; PTHR10322:SF23; DNA POLYMERASE DELTA CATALYTIC SUBUNIT; 1.
DR Pfam; PF00136; DNA_pol_B; 1.
DR PRINTS; PR00106; DNAPOLB.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS00116; DNA_POLYMERASE_B; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW DNA-directed DNA polymerase {ECO:0000256|ARBA:ARBA00022932};
KW Nucleotidyltransferase {ECO:0000313|EMBL:OYU42523.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000216392};
KW Transferase {ECO:0000313|EMBL:OYU42523.1}.
FT DOMAIN 13..381
FT /note="DNA-directed DNA polymerase family B
FT multifunctional"
FT /evidence="ECO:0000259|Pfam:PF00136"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:OYU42523.1"
SQ SEQUENCE 399 AA; 45787 MW; BF7C13A39EDAAEE1 CRC64;
VAPNVGEIQR KASPGGYVMD SEPGFYDSVL VLDYKSLYPS IIRTFCVDPV GYAEGQWASN
TENLIKGPMG TLFSRERHCL PYIVTSLWRS RDEAKRAKNE PLSQTLKLLM NSFAGVLGAS
ECRFFSPELV SAVTLRGHEI VKRTQVFVEN RGYKAIYGDT DSIFLWLGRL HSDSEAHALA
TELVRDINLW WTHILHEEQG LENFLEIEFD THYKKFFMPT IRGSDVGSKK RYAGLSTDAD
GNEEMIFRGL EMARSDWTLL ARRFQEGLLS RIFHGEPYRE FVSSYAQATL EGSMDELLVY
RKRLRHRLDA YVVNIPPQVR AARTADDYNL RMGRPAQYQN GGWIEYLMTK NGPEPLENHQ
SRLDYEHYLN KQLKPIADAI LQPLGENFSS LISHQRDLF
//
