ID   A0A257GYU0_9BURK        Unreviewed;       310 AA.
AC   A0A257GYU0;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Dihydrodipicolinate synthase family protein {ECO:0000313|EMBL:OYU43553.1};
GN   ORFNames=CFE44_17740 {ECO:0000313|EMBL:OYU43553.1};
OS   Burkholderiales bacterium PBB4.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales.
OX   NCBI_TaxID=2015566 {ECO:0000313|EMBL:OYU43553.1, ECO:0000313|Proteomes:UP000216392};
RN   [1] {ECO:0000313|EMBL:OYU43553.1, ECO:0000313|Proteomes:UP000216392}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PBB4 {ECO:0000313|EMBL:OYU43553.1};
RA   Kojadinovic M., Villain A., Puppo C., Fon Sing S., Prioretti L., Hubert P.,
RA   Gregori G., Zhang Y., Sassi J.-F., Claverie J.-M., Blanc G., Gontero B.;
RT   "A metagenomic investigation of the 'star' freshwater diatom Asterionella
RT   formosa and its bacterial cohort.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DapA family.
CC       {ECO:0000256|PIRNR:PIRNR001365}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OYU43553.1}.
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DR   EMBL; NKIJ01000595; OYU43553.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A257GYU0; -.
DR   Proteomes; UP000216392; Unassembled WGS sequence.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   CDD; cd00408; DHDPS-like; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR002220; DapA-like.
DR   PANTHER; PTHR12128:SF74; BLL4423 PROTEIN; 1.
DR   PANTHER; PTHR12128; DIHYDRODIPICOLINATE SYNTHASE; 1.
DR   Pfam; PF00701; DHDPS; 1.
DR   PIRSF; PIRSF001365; DHDPS; 1.
DR   PRINTS; PR00146; DHPICSNTHASE.
DR   SMART; SM01130; DHDPS; 1.
DR   SUPFAM; SSF51569; Aldolase; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000256|PIRNR:PIRNR001365};
KW   Reference proteome {ECO:0000313|Proteomes:UP000216392}.
FT   ACT_SITE        144
FT                   /note="Proton donor/acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT   ACT_SITE        172
FT                   /note="Schiff-base intermediate with substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-1"
FT   BINDING         214
FT                   /ligand="pyruvate"
FT                   /ligand_id="ChEBI:CHEBI:15361"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR001365-2"
SQ   SEQUENCE   310 AA;  34276 MW;  7D41C93609457E31 CRC64;
     MASTSRTRKG TWTGVFPAIT TQMHKDGSLD LDATARHTEI LIKSGISGLV YLGSLGETQT
     LSAEEKRLLI KEMVGVVKGR IPVVSGVAES SLLEATRYVR DCEKLGADGY MVMPAMSYKT
     TDPEESMGYL RGVAKATGLP IMIYNNPISY GNDITPEMFA KLADVKNFTS LKESSGNTRR
     ITDLRNTVGD RYSIFTGVDD LALESAVLGI DGWVAGTGIA FPEENQYLWD LMQAGEWKKA
     LEIYRWFTPL LHLDVNIKFV QNIKLCVQEC GLGTEWVRAP RTLLKGAERK AVLKVIHDGI
     ANRPKLPKRK
//