ID   A0A257H3E8_9BURK        Unreviewed;       421 AA.
AC   A0A257H3E8;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   13-SEP-2023, entry version 11.
DE   SubName: Full=Penicillin-binding protein 2 {ECO:0000313|EMBL:OYU44350.1};
GN   Name=mrdA {ECO:0000313|EMBL:OYU44350.1};
GN   ORFNames=CFE44_13420 {ECO:0000313|EMBL:OYU44350.1};
OS   Burkholderiales bacterium PBB4.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales.
OX   NCBI_TaxID=2015566 {ECO:0000313|EMBL:OYU44350.1, ECO:0000313|Proteomes:UP000216392};
RN   [1] {ECO:0000313|EMBL:OYU44350.1, ECO:0000313|Proteomes:UP000216392}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PBB4 {ECO:0000313|EMBL:OYU44350.1};
RA   Kojadinovic M., Villain A., Puppo C., Fon Sing S., Prioretti L., Hubert P.,
RA   Gregori G., Zhang Y., Sassi J.-F., Claverie J.-M., Blanc G., Gontero B.;
RT   "A metagenomic investigation of the 'star' freshwater diatom Asterionella
RT   formosa and its bacterial cohort.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OYU44350.1}.
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DR   EMBL; NKIJ01000361; OYU44350.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A257H3E8; -.
DR   Proteomes; UP000216392; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR   GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   InterPro; IPR017790; Penicillin-binding_protein_2.
DR   NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000216392}.
FT   DOMAIN          33..372
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
SQ   SEQUENCE   421 AA;  45727 MW;  F8781895264A9056 CRC64;
     MASTPSTPGN MVVLSIDIKL QKLVEDMFGD RRGALVAIDP RNGEVLAFVS KPTFDSNLFV
     EGIDQDNWQM LNESLDKPLL NRALRGTYPP GSTYKPFMAL AALELGQRTP ATLVNDPGFF
     MFGGHRFGSP ETDKTGIMDM RASIVHSSNA YYYSLANELG VDRMYDFMAP LGFGQITGID
     IFGEVKGVLP SQAWKKKYYK RPEQQRWYAG ETISLGIGQG YNNFTMLQLA QATSILANGG
     IKHKPQLVIG TQDASTHIRV DLPKPPAQDL GFKPEHVEVI RQAMAAVTLE GTSARVFAGA
     AYQSAGKTGT AQAVGLSQKE KYNAAKMEER QRDHSLYSAF APADKPQIAL AVIVENAGFG
     SASAAPIARR VFDYVLLGQY PNAEDLAQVS KGLATAPLGK PLVAAEVPWP REPIKVEATK
     P
//