ID A0A257IUN9_9BACT Unreviewed; 387 AA.
AC A0A257IUN9;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE RecName: Full=isochorismate synthase {ECO:0000256|ARBA:ARBA00012824};
DE EC=5.4.4.2 {ECO:0000256|ARBA:ARBA00012824};
DE AltName: Full=Isochorismate mutase {ECO:0000256|ARBA:ARBA00041564};
GN ORFNames=CFE22_08745 {ECO:0000313|EMBL:OYU66564.1};
OS Cytophagaceae bacterium BCCC1.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Cytophagaceae.
OX NCBI_TaxID=2015573 {ECO:0000313|EMBL:OYU66564.1, ECO:0000313|Proteomes:UP000215757};
RN [1] {ECO:0000313|EMBL:OYU66564.1, ECO:0000313|Proteomes:UP000215757}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BCCC1 {ECO:0000313|EMBL:OYU66564.1};
RA Kojadinovic M., Villain A., Puppo C., Fon Sing S., Prioretti L., Hubert P.,
RA Gregori G., Zhang Y., Sassi J.-F., Claverie J.-M., Blanc G., Gontero B.;
RT "A metagenomic investigation of the 'star' freshwater diatom Asterionella
RT formosa and its bacterial cohort.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=chorismate = isochorismate; Xref=Rhea:RHEA:18985,
CC ChEBI:CHEBI:29748, ChEBI:CHEBI:29780; EC=5.4.4.2;
CC Evidence={ECO:0000256|ARBA:ARBA00000799};
CC -!- SIMILARITY: Belongs to the isochorismate synthase family.
CC {ECO:0000256|ARBA:ARBA00005297}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYU66564.1}.
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DR EMBL; NKJF01000016; OYU66564.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A257IUN9; -.
DR Proteomes; UP000215757; Unassembled WGS sequence.
DR GO; GO:0008909; F:isochorismate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR Gene3D; 3.60.120.10; Anthranilate synthase; 1.
DR InterPro; IPR005801; ADC_synthase.
DR InterPro; IPR015890; Chorismate_C.
DR InterPro; IPR004561; IsoChor_synthase.
DR NCBIfam; TIGR00543; isochor_syn; 1.
DR PANTHER; PTHR42839; ISOCHORISMATE SYNTHASE ENTC; 1.
DR PANTHER; PTHR42839:SF2; ISOCHORISMATE SYNTHASE ENTC; 1.
DR Pfam; PF00425; Chorismate_bind; 1.
DR SUPFAM; SSF56322; ADC synthase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235};
KW Reference proteome {ECO:0000313|Proteomes:UP000215757}.
FT DOMAIN 120..378
FT /note="Chorismate-utilising enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF00425"
SQ SEQUENCE 387 AA; 44001 MW; 72E453FB23C4CE1C CRC64;
MIATKSSINI DLFLENCIEQ KFPFALYKMP NTSQVKLIVS FDKSENRKRI DFDECGSGFV
MAPYDKENEL PYFYKNDFEV DIKDFSDIEV PEYLKDKFEL SKYILSENFS LKGKNDSCDS
QSHKKKVEAV IVCIQNGEAK KVVLSRKKHL GEIAENNLLK GFQNLSKSNP SGFVSLVNVP
WKNQIWLGAS PEILVSQDEN GMFKTVSLAG TQSAIDKNGN EIRPLDALWS HKEIEEQAFV
GRYIINCLKK IRVREFLEEG PKTVKAGNLL HLNTSYSIDT KEINFSNLSS VMLDLLHPTP
AVCGMPKEAA ESIIEKIEEY DREFYSGYLG PVNIDNNSHL FVNIRTLKIE NQQVYAFAGG
GITEDSDPEK EWNETEIKLQ TILRSFS
//
