ID   A0A257J7G8_9PROT        Unreviewed;       219 AA.
AC   A0A257J7G8;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=Hexapeptide transferase {ECO:0000313|EMBL:OYU70475.1};
GN   ORFNames=CFE28_11035 {ECO:0000313|EMBL:OYU70475.1};
OS   Alphaproteobacteria bacterium PA2.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria.
OX   NCBI_TaxID=2015570 {ECO:0000313|EMBL:OYU70475.1, ECO:0000313|Proteomes:UP000215921};
RN   [1] {ECO:0000313|EMBL:OYU70475.1, ECO:0000313|Proteomes:UP000215921}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PA2 {ECO:0000313|EMBL:OYU70475.1};
RA   Kojadinovic M., Villain A., Puppo C., Fon Sing S., Prioretti L., Hubert P.,
RA   Gregori G., Zhang Y., Sassi J.-F., Claverie J.-M., Blanc G., Gontero B.;
RT   "A metagenomic investigation of the 'star' freshwater diatom Asterionella
RT   formosa and its bacterial cohort.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OYU70475.1}.
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DR   EMBL; NKIZ01000001; OYU70475.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A257J7G8; -.
DR   Proteomes; UP000215921; Unassembled WGS sequence.
DR   GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR   CDD; cd03360; LbH_AT_putative; 1.
DR   Gene3D; 3.40.50.20; -; 1.
DR   Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR   InterPro; IPR020019; AcTrfase_PglD-like.
DR   InterPro; IPR001451; Hexapep.
DR   InterPro; IPR018357; Hexapep_transf_CS.
DR   InterPro; IPR041561; PglD_N.
DR   InterPro; IPR011004; Trimer_LpxA-like_sf.
DR   NCBIfam; TIGR03570; NeuD_NnaD; 1.
DR   PANTHER; PTHR43300; ACETYLTRANSFERASE; 1.
DR   PANTHER; PTHR43300:SF7; UDP-N-ACETYLBACILLOSAMINE N-ACETYLTRANSFERASE; 1.
DR   Pfam; PF00132; Hexapep; 1.
DR   Pfam; PF17836; PglD_N; 1.
DR   SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
DR   PROSITE; PS00101; HEXAPEP_TRANSFERASES; 1.
PE   4: Predicted;
KW   Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215921};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:OYU70475.1}.
FT   DOMAIN          10..82
FT                   /note="PglD N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF17836"
FT   ACT_SITE        141
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR620019-1"
FT   BINDING         74
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR620019-2"
FT   BINDING         150
FT                   /ligand="acetyl-CoA"
FT                   /ligand_id="ChEBI:CHEBI:57288"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR620019-2"
FT   SITE            142
FT                   /note="Increases basicity of active site His"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR620019-1"
SQ   SEQUENCE   219 AA;  21537 MW;  6C6F1367BE411469 CRC64;
     MPGPDPKDAV VIIGAGGHAK VVIDLLNSSG VPIFGLTDVD GSPRRILGAP VLGNDEILPS
     LFTQGVRHVF VALGDNQLRL AMGARVHALG FDLVNAISPR ATISPSARLG RGVAIMAGAV
     INADAQIGDL AIINTGAGVD HDTFVGRGSH VGPGAAVAGG VHIGSGALLG VGSSVAPGCS
     IGEGAIIGAG ACVIDDIAPD LVAVGVPARA KGEIQKGRP
//