ID   A0A257KDY6_9FLAO        Unreviewed;       800 AA.
AC   A0A257KDY6;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Transketolase {ECO:0000313|EMBL:OYU85448.1};
GN   ORFNames=CFE24_01820 {ECO:0000313|EMBL:OYU85448.1};
OS   Flavobacterium sp. BFFFF2.
OC   Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC   Flavobacteriaceae; Flavobacterium.
OX   NCBI_TaxID=2015558 {ECO:0000313|EMBL:OYU85448.1, ECO:0000313|Proteomes:UP000216176};
RN   [1] {ECO:0000313|EMBL:OYU85448.1, ECO:0000313|Proteomes:UP000216176}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BFFFF2 {ECO:0000313|EMBL:OYU85448.1};
RA   Kojadinovic M., Villain A., Puppo C., Fon Sing S., Prioretti L., Hubert P.,
RA   Gregori G., Zhang Y., Sassi J.-F., Claverie J.-M., Blanc G., Gontero B.;
RT   "A metagenomic investigation of the 'star' freshwater diatom Asterionella
RT   formosa and its bacterial cohort.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC         Evidence={ECO:0000256|ARBA:ARBA00001964};
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OYU85448.1}.
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DR   EMBL; NKJD01000003; OYU85448.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A257KDY6; -.
DR   Proteomes; UP000216176; Unassembled WGS sequence.
DR   GO; GO:0016624; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; IEA:InterPro.
DR   CDD; cd02000; TPP_E1_PDC_ADC_BCADC; 1.
DR   Gene3D; 3.40.50.920; -; 1.
DR   Gene3D; 3.40.50.970; -; 2.
DR   InterPro; IPR001017; DH_E1.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR   InterPro; IPR033248; Transketolase_C.
DR   PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR   Pfam; PF00676; E1_dh; 1.
DR   Pfam; PF02779; Transket_pyr; 1.
DR   Pfam; PF02780; Transketolase_C; 1.
DR   SMART; SM00861; Transket_pyr; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000216176}.
FT   DOMAIN          470..644
FT                   /note="Transketolase-like pyrimidine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00861"
SQ   SEQUENCE   800 AA;  88969 MW;  91C79C5232C8FFF1 CRC64;
     MEQDLHPTPK AALSFDDFKQ EVLHDYQLAV LSRECSLLGR KEVLTGKAKF GIFGDGKEVP
     QLAMAKAFKM GDFRSGYYRD QTFMMAIGQL TVEQFFAGLY GHADIAHDPM SGGRQMGGHF
     ATHSLDENGQ WKNLTEQKNS SADISPTAGQ MPRLLGLAQA SKVYRHVPEL AQATSFSNGG
     NEVAWGTIGN ASTSEGLFFE TINAAGVLQV PMVMSVWDDE YGISVHARHQ TTKENISDIL
     RGFQREDNRP GYEIINVKGW DYPALVEAYE KASQIARNEH VPVLIHVNEL TQPQGHSTSG
     SHERYKSAER LEWEREFDCI RQMRLWMVAN GMATDNELDA IDKAAKKQVN EGKKAAWAAY
     QTPIKNEQTE LVQLLNHWAT ESIQGVFIQK MATDLAAIKE PIRKDILVTA RKVLRLVRKE
     AISAAVSAWA TNYQQTVAPN FSSHLFTNST QSPQYATAVL PVYDESAEEV DGRVVLRDNF
     KTLFEAHPEV LIFGEDAGKI GDVNQGLENM QEWFGEHRVS DTGIREATIL GQGIGMAMRG
     LRPIAEIQYL DYLLYALQIM SDDLATLAYR TAGRQKAPLI IRTRGHRLEG IWHSGSPMGM
     IIHALRGIHV LVPRDMTRAA GFYNTLLAGD EPALVVECLN GYRLKEKLPT NLGQFKTPLG
     EVETLRQGTD LTIVSYGSTL RLVMQAAQEL AAIGIEAAVI DVQSLLPFDK AHNIAKSLEK
     TNRLLVVDED VPGGASAYIL QQILEQQNGY YHLDSKPQTL TAKAHRPAYG TDGDYFSKPS
     TEDIYDAVLQ MMEESFPGRY
//