ID A0A257LCG4_9BACT Unreviewed; 634 AA.
AC A0A257LCG4;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN Name=acs {ECO:0000313|EMBL:OYU97334.1};
GN ORFNames=CFE21_03310 {ECO:0000313|EMBL:OYU97334.1};
OS Bacteroidetes bacterium B1(2017).
OC Bacteria; Bacteroidota.
OX NCBI_TaxID=2015582 {ECO:0000313|EMBL:OYU97334.1, ECO:0000313|Proteomes:UP000216329};
RN [1] {ECO:0000313|EMBL:OYU97334.1, ECO:0000313|Proteomes:UP000216329}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B1 {ECO:0000313|EMBL:OYU97334.1};
RA Kojadinovic M., Villain A., Puppo C., Fon Sing S., Prioretti L., Hubert P.,
RA Gregori G., Zhang Y., Sassi J.-F., Claverie J.-M., Blanc G., Gontero B.;
RT "A metagenomic investigation of the 'star' freshwater diatom Asterionella
RT formosa and its bacterial cohort.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYU97334.1}.
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DR EMBL; NKJG01000001; OYU97334.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A257LCG4; -.
DR Proteomes; UP000216329; Unassembled WGS sequence.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR CDD; cd05966; ACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:OYU97334.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000216329}.
FT DOMAIN 11..66
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 68..454
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 516..594
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 634 AA; 71077 MW; 0DA1DD8A2965A7F1 CRC64;
MIPVIKSFSQ YQEEYQRSID SPEQFWDEVA ETFLWKKKWE KTLNWNFTEP KVEWFAGGKL
NISENCLDRH IEARGEQTAI IWEPNNPADA SRKVTYSELH VLVMKFANVL TSLGVKKGDR
VCIYMPMIPE AAVAMLACAR VGAIHSVVFA GFSSQSLTDR ITDAECKVLL TADGMIRGEK
KIDLKQIADE AMKNSPSIET CVVYNHKGFD ITMQQGRDYD WQALMNTASN THQAEEMDSE
DPLFILYTSG STGKPKGVLH TTAGYMVYTA YTFKNVFQYE DKDVFCCTAD IGWVTGHSYI
VYGPLLSGAT TLMFEGIPSW PSPGRFWELI DKHQVNVFYT APTAIRSLEV FGLEPFEGKN
LSSLKVLGSV GEPINEEAWH WYHENVGKGK CPIVDTWWQT ETGGILISPL ANITPLKPAF
ATLPLPGVQL AIVDEKGQEV LGNSVEGNLC IKFPWPGMSR SIYGDHERFR TTYFSTYENK
YFTGDGCKRD EDGYIRITGR VDDVINVSGH RIGTGEVEDA MNEHGYIIES AVVGYPHDIK
GQGIWAFVIC DREHHSYEEL CAEAKAHVTK VIGPFARPDR IQVVKALPKT RSGKIMRRIL
RKIAEGDISN LGDTSTLIDP TVVDLIKAGA EEIR
//
