ID A0A257LF41_9BURK Unreviewed; 392 AA.
AC A0A257LF41;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 08-NOV-2023, entry version 17.
DE SubName: Full=Acetyl-CoA acetyltransferase {ECO:0000313|EMBL:OYU98223.1};
DE EC=2.3.1.9 {ECO:0000313|EMBL:OYU98223.1};
GN ORFNames=CFE45_17305 {ECO:0000313|EMBL:OYU98223.1};
OS Burkholderiales bacterium PBB5.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales.
OX NCBI_TaxID=2015567 {ECO:0000313|EMBL:OYU98223.1, ECO:0000313|Proteomes:UP000215735};
RN [1] {ECO:0000313|EMBL:OYU98223.1, ECO:0000313|Proteomes:UP000215735}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PBB5 {ECO:0000313|EMBL:OYU98223.1};
RA Kojadinovic M., Villain A., Puppo C., Fon Sing S., Prioretti L., Hubert P.,
RA Gregori G., Zhang Y., Sassi J.-F., Claverie J.-M., Blanc G., Gontero B.;
RT "A metagenomic investigation of the 'star' freshwater diatom Asterionella
RT formosa and its bacterial cohort.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYU98223.1}.
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DR EMBL; NKII01000814; OYU98223.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A257LF41; -.
DR Proteomes; UP000215735; Unassembled WGS sequence.
DR GO; GO:0003985; F:acetyl-CoA C-acetyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919:SF138; ACETYL-COA C-ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|RuleBase:RU003557,
KW ECO:0000313|EMBL:OYU98223.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000215735};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:OYU98223.1}.
FT DOMAIN 5..262
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 269..390
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 89
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 348
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 378
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 392 AA; 40555 MW; 7848485E79380CC9 CRC64;
MADSIVIVSA ARTPIGGLLG DFSSLAAWEL GGVAIKAAVE RAGVPGDAID EVLMGNCLMA
GQGQAPARQA MRRAGVPDSA GAVTLSKMCG SGMRAMMFGH DMLAAGSANV VVAGGMESMT
NAPHLMFARK GVKYGAAQLF DHMAIDGLED AYERGKAMGV FAEQCVAKYG FSREAQDQFA
ITSTLRSQQA NQDGSFDWEV APVSLPGKAG DTVVRHDEQP FKAKLDKIAG LKPAFKKDGT
ITAATSSSIS DGAAALVLVR ESTATQLGLK PIARIAGHAV HAQAPEWFST APAGAIDKVL
RKAGWDAKSV NLWEVNEAFA AVTMAAMAEF KLPHEIVNVH GGACALGHPI GASGARIVVT
LLGAMRKQQV RRGVAALCIG GGEATAMAVE LL
//
