ID A0A257LF54_9BACT Unreviewed; 456 AA.
AC A0A257LF54;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE RecName: Full=Carboxypeptidase Q {ECO:0000256|ARBA:ARBA00014116};
DE AltName: Full=Plasma glutamate carboxypeptidase {ECO:0000256|ARBA:ARBA00033328};
GN ORFNames=CFE21_04690 {ECO:0000313|EMBL:OYU97595.1};
OS Bacteroidetes bacterium B1(2017).
OC Bacteria; Bacteroidota.
OX NCBI_TaxID=2015582 {ECO:0000313|EMBL:OYU97595.1, ECO:0000313|Proteomes:UP000216329};
RN [1] {ECO:0000313|EMBL:OYU97595.1, ECO:0000313|Proteomes:UP000216329}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=B1 {ECO:0000313|EMBL:OYU97595.1};
RA Kojadinovic M., Villain A., Puppo C., Fon Sing S., Prioretti L., Hubert P.,
RA Gregori G., Zhang Y., Sassi J.-F., Claverie J.-M., Blanc G., Gontero B.;
RT "A metagenomic investigation of the 'star' freshwater diatom Asterionella
RT formosa and its bacterial cohort.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homodimer. The monomeric form is inactive while the homodimer
CC is active. {ECO:0000256|ARBA:ARBA00025833}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum
CC {ECO:0000256|ARBA:ARBA00004240}. Golgi apparatus
CC {ECO:0000256|ARBA:ARBA00004555}. Lysosome
CC {ECO:0000256|ARBA:ARBA00004371}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYU97595.1}.
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DR EMBL; NKJG01000001; OYU97595.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A257LF54; -.
DR Proteomes; UP000216329; Unassembled WGS sequence.
DR GO; GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.
DR GO; GO:0004180; F:carboxypeptidase activity; IEA:UniProtKB-KW.
DR GO; GO:0070573; F:metallodipeptidase activity; IEA:InterPro.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR039866; CPQ.
DR InterPro; IPR007484; Peptidase_M28.
DR PANTHER; PTHR12053:SF3; CARBOXYPEPTIDASE Q; 1.
DR PANTHER; PTHR12053; PROTEASE FAMILY M28 PLASMA GLUTAMATE CARBOXYPEPTIDASE-RELATED; 1.
DR Pfam; PF04389; Peptidase_M28; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE 4: Predicted;
KW Carboxypeptidase {ECO:0000256|ARBA:ARBA00022645};
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022645};
KW Lysosome {ECO:0000256|ARBA:ARBA00023228};
KW Protease {ECO:0000256|ARBA:ARBA00022645};
KW Reference proteome {ECO:0000313|Proteomes:UP000216329};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..456
FT /note="Carboxypeptidase Q"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5013373472"
FT DOMAIN 259..447
FT /note="Peptidase M28"
FT /evidence="ECO:0000259|Pfam:PF04389"
SQ SEQUENCE 456 AA; 49549 MW; 820726AA77303B3A CRC64;
MKNKILFLIG LMAFLPNLLI AQSDSLQVRK IVNQILLDGQ CYKRLDYLSN SIGGRLSGSK
EAEAAVNYTF DILKKEGFDS VWLQPVLVPH WVRGQKEEAW YWVGKKKIIP TICALGGSCG
TDKKGLEAEV IEVKSIKELQ ALGSEKIKGK IVFYNRPMNP LFIKTFEAYG DAVDQRAAGA
VEASKLGAVG VIVRSMGSNI DKHPHTGVMR VLPEVKQIPA CAISTFDAEE LSLALKANSR
LTFSFKMSCA TLADVWSYNV VAQINGSEKA DEIIVVGGHL DSWDNGDGAH DDGAGVVQSM
EVLHTYKALG LKPKRSIRCV LFMNEENGAK GASAYAAFAK QNQEKHIAAI ESDAGGFTPR
NFGATTDDAK LAKLRTWAPL LKQYGIEEVL SSGGGVDIGP LKEQGCTLIG FGPDSQRYFD
VHHTAVDTFD KVSKRELELG AANIAALVWL ISENGL
//
