ID   A0A257LF66_9BACT        Unreviewed;       139 AA.
AC   A0A257LF66;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   SubName: Full=3-hydroxy-3-methylglutaryl-CoA reductase {ECO:0000313|EMBL:OYU98297.1};
DE   Flags: Fragment;
GN   ORFNames=CFE26_27840 {ECO:0000313|EMBL:OYU98297.1};
OS   Verrucomicrobiales bacterium VVV1.
OC   Bacteria; Verrucomicrobiota; Verrucomicrobiae; Verrucomicrobiales.
OX   NCBI_TaxID=2015575 {ECO:0000313|EMBL:OYU98297.1, ECO:0000313|Proteomes:UP000216473};
RN   [1] {ECO:0000313|EMBL:OYU98297.1, ECO:0000313|Proteomes:UP000216473}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VVV1 {ECO:0000313|EMBL:OYU98297.1};
RA   Kojadinovic M., Villain A., Puppo C., Fon Sing S., Prioretti L., Hubert P.,
RA   Gregori G., Zhang Y., Sassi J.-F., Claverie J.-M., Blanc G., Gontero B.;
RT   "A metagenomic investigation of the 'star' freshwater diatom Asterionella
RT   formosa and its bacterial cohort.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OYU98297.1}.
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DR   EMBL; NKJB01002094; OYU98297.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A257LF66; -.
DR   Proteomes; UP000216473; Unassembled WGS sequence.
DR   GO; GO:0004420; F:hydroxymethylglutaryl-CoA reductase (NADPH) activity; IEA:InterPro.
DR   GO; GO:0015936; P:coenzyme A metabolic process; IEA:InterPro.
DR   InterPro; IPR002202; HMG_CoA_Rdtase.
DR   InterPro; IPR023074; HMG_CoA_Rdtase_cat_sf.
DR   InterPro; IPR023076; HMG_CoA_Rdtase_CS.
DR   InterPro; IPR009029; HMG_CoA_Rdtase_sub-bd_dom_sf.
DR   PANTHER; PTHR10572; 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE; 1.
DR   PANTHER; PTHR10572:SF24; 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE; 1.
DR   Pfam; PF00368; HMG-CoA_red; 1.
DR   PRINTS; PR00071; HMGCOARDTASE.
DR   SUPFAM; SSF56542; Substrate-binding domain of HMG-CoA reductase; 1.
DR   PROSITE; PS00318; HMG_COA_REDUCTASE_2; 1.
DR   PROSITE; PS50065; HMG_COA_REDUCTASE_4; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000216473}.
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:OYU98297.1"
SQ   SEQUENCE   139 AA;  13947 MW;  9840D990F2072F94 CRC64;
     EYWRVSVIGG VLSGTIGVHG HFANGLAALY LATGQDVACV AESAVGVTRF ECMPNGDLYA
     AVTLPGIMVG TVGGGTGLPS QHACLELMGL AGSGHAGALA EVCAGLLLAG ELSIIGALSA
     GHFSRAHRKL ARDRTLPPP
//