ID   A0A257LGK7_9BURK        Unreviewed;       405 AA.
AC   A0A257LGK7;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=Homoaconitate hydratase {ECO:0000256|ARBA:ARBA00032706};
GN   ORFNames=CFE45_15140 {ECO:0000313|EMBL:OYU98797.1};
OS   Burkholderiales bacterium PBB5.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales.
OX   NCBI_TaxID=2015567 {ECO:0000313|EMBL:OYU98797.1, ECO:0000313|Proteomes:UP000215735};
RN   [1] {ECO:0000313|EMBL:OYU98797.1, ECO:0000313|Proteomes:UP000215735}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PBB5 {ECO:0000313|EMBL:OYU98797.1};
RA   Kojadinovic M., Villain A., Puppo C., Fon Sing S., Prioretti L., Hubert P.,
RA   Gregori G., Zhang Y., Sassi J.-F., Claverie J.-M., Blanc G., Gontero B.;
RT   "A metagenomic investigation of the 'star' freshwater diatom Asterionella
RT   formosa and its bacterial cohort.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OYU98797.1}.
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DR   EMBL; NKII01000667; OYU98797.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A257LGK7; -.
DR   Proteomes; UP000215735; Unassembled WGS sequence.
DR   GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:1901564; P:organonitrogen compound metabolic process; IEA:UniProt.
DR   GO; GO:0043436; P:oxoacid metabolic process; IEA:UniProt.
DR   Gene3D; 3.30.499.10; Aconitase, domain 3; 2.
DR   InterPro; IPR015931; Acnase/IPM_dHydase_lsu_aba_1/3.
DR   InterPro; IPR001030; Acoase/IPM_deHydtase_lsu_aba.
DR   InterPro; IPR036008; Aconitase_4Fe-4S_dom.
DR   PANTHER; PTHR43822:SF25; HOMOACONITASE, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR43822; HOMOACONITASE, MITOCHONDRIAL-RELATED; 1.
DR   Pfam; PF00330; Aconitase; 2.
DR   SUPFAM; SSF53732; Aconitase iron-sulfur domain; 1.
PE   4: Predicted;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215735}.
FT   DOMAIN          81..232
FT                   /note="Aconitase/3-isopropylmalate dehydratase large
FT                   subunit alpha/beta/alpha"
FT                   /evidence="ECO:0000259|Pfam:PF00330"
FT   DOMAIN          263..386
FT                   /note="Aconitase/3-isopropylmalate dehydratase large
FT                   subunit alpha/beta/alpha"
FT                   /evidence="ECO:0000259|Pfam:PF00330"
SQ   SEQUENCE   405 AA;  42894 MW;  5599C60C48AC42D3 CRC64;
     MGQTITEKIL ARVSGRASVR PGDEILAEPD FVIAYDFPGY TDVFFREAKE DFGVDQVSKP
     ERFVLFIDHM VPATAPKEEE LHKVTRAWGA KQGVPVHERE GIGHQVSAEL GYATPGAFAV
     HFDGHVSQLG AFGTLAMGVR KGVLEAFVSD DMAIKVPATI KVVITGTLQP GVMARDVFHH
     LVRVMGPASC RFKVVELCGP VIDAMSIEGR QTICGQAMFL GATTMLIAPD AEYEQVVTVD
     VSGLQPIVVA PPSPANTRDL SEYAGLEVHT GYLGSCASGR LEDLRAAAAV LKGRKIPAGF
     QLHVVPTSQA IMSAAAREGL ISTLVDAGAF ISSSSCDYCY GRIATMTDGQ RAVSTGTLNT
     PGRMGSPDSE IFICNAAVVA ASALNGCITD PRPYLAEAIA RGDVL
//