ID   A0A257M3K2_9BACT        Unreviewed;       812 AA.
AC   A0A257M3K2;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN   ORFNames=CFE26_05870 {ECO:0000313|EMBL:OYV06518.1};
OS   Verrucomicrobiales bacterium VVV1.
OC   Bacteria; Verrucomicrobiota; Verrucomicrobiae; Verrucomicrobiales.
OX   NCBI_TaxID=2015575 {ECO:0000313|EMBL:OYV06518.1, ECO:0000313|Proteomes:UP000216473};
RN   [1] {ECO:0000313|EMBL:OYV06518.1, ECO:0000313|Proteomes:UP000216473}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=VVV1 {ECO:0000313|EMBL:OYV06518.1};
RA   Kojadinovic M., Villain A., Puppo C., Fon Sing S., Prioretti L., Hubert P.,
RA   Gregori G., Zhang Y., Sassi J.-F., Claverie J.-M., Blanc G., Gontero B.;
RT   "A metagenomic investigation of the 'star' freshwater diatom Asterionella
RT   formosa and its bacterial cohort.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OYV06518.1}.
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DR   EMBL; NKJB01000138; OYV06518.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A257M3K2; -.
DR   Proteomes; UP000216473; Unassembled WGS sequence.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR   PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF13676; TIR_2; 1.
DR   Pfam; PF13374; TPR_10; 1.
DR   Pfam; PF13424; TPR_12; 1.
DR   SMART; SM00255; TIR; 1.
DR   SMART; SM00028; TPR; 3.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   PROSITE; PS50104; TIR; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000216473}.
FT   DOMAIN          9..141
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
SQ   SEQUENCE   812 AA;  88764 MW;  A746C8E240B4ABEF CRC64;
     MAMSSQSTED IDFFVSYTGK DQAWAEWIAW HLEANGHKTV IQAWDFKSGG VFPGDMHRAL
     KRSTRVLAVI SPDYMASNFC APEWQAAFAE DPTGEKGILV CVRVADFKPD GLLRGRTYID
     LVGLDEKKAL ELLLARLDNK RSKPDAAPAF PASSQETAPA FPGAASFTPL YTSIPHNLPT
     LQPFFGREDE LKKIADALDP DSRTWGALID GPGGMGKTSL AVRAAYDASP EVFKKIIFIS
     LKTRELDDDG LRDLSGFILS GLVELLNELA RELGHADIVK APEDQRPRLL LDKLRGTQTL
     LVLDNLESLI KSERDTLFTF VKKLPTGCKA ILTSRGRIGS GAEELILEAL SQEAALATLA
     ELATHNPLLA QTSEAERLVL YRETAGKPLL LRWTAGQLGR GHCLTFTDAL HFIRSCPQGN
     DPLEFIFGDL VEDFDAHETK ALCALTYFTL PAEVKHVAAI AGLPEPETDL ALRKLTVRSL
     AVPTDELKTF TLVPMVADFL RKKKPEVVAE TGDRLEKRAY ALIMENGYEN HDRYPALEAA
     WPGIAPALAL FLAGDNARLQ TVCDALQNFL NFQGRWDERL ALCETAEAKA VAAADHERAG
     WRAYHVGMIH HKRQQADAVL TCSDRAAAHW DRAKAGARER AAAIQMRGLG HRLKKDYPAA
     FAAYREALDL HRSLAAESKD VASGLNSLAT AEMESGDFTA AEEHYLEALR GARAVGFTEG
     VAIFTGNLAG LALDREDWSA AETLAREALP LSEAIHRQEL IASNNHHLAY ALVRQGKAAE
     ALPHARRAVE IFTHLGSPDL AGALAILAEC QA
//