ID   A0A257R5N0_9PROT        Unreviewed;       524 AA.
AC   A0A257R5N0;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Heparinase {ECO:0000313|EMBL:OYV56324.1};
GN   ORFNames=B7Z76_06610 {ECO:0000313|EMBL:OYV56324.1};
OS   Acidiphilium sp. 20-67-58.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC   Acetobacteraceae; Acidiphilium.
OX   NCBI_TaxID=1970291 {ECO:0000313|EMBL:OYV56324.1, ECO:0000313|Proteomes:UP000216756};
RN   [1] {ECO:0000313|EMBL:OYV56324.1, ECO:0000313|Proteomes:UP000216756}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=20-67-58 {ECO:0000313|EMBL:OYV56324.1};
RA   Kantor R.S., Colenbrander Nelson T., Marshall S., Bennett D., Apte S.,
RA   Camacho D., Thomas B.C., Warren L.A., Banfield J.F.;
RT   "Lifting the veil on microbial sulfur biogeochemistry in mining
RT   wastewaters.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000256|ARBA:ARBA00004418}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OYV56324.1}.
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DR   EMBL; NCAS01000012; OYV56324.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A257R5N0; -.
DR   Proteomes; UP000216756; Unassembled WGS sequence.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.70.98.70; -; 1.
DR   Gene3D; 1.50.10.100; Chondroitin AC/alginate lyase; 1.
DR   InterPro; IPR008929; Chondroitin_lyas.
DR   InterPro; IPR012480; Hepar_II_III.
DR   InterPro; IPR031680; Hepar_II_III_N.
DR   PANTHER; PTHR39210; HEPARIN-SULFATE LYASE; 1.
DR   PANTHER; PTHR39210:SF1; HEPARIN-SULFATE LYASE; 1.
DR   Pfam; PF07940; Hepar_II_III; 1.
DR   Pfam; PF16889; Hepar_II_III_N; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Periplasm {ECO:0000256|ARBA:ARBA00022764};
KW   Signal {ECO:0000256|ARBA:ARBA00022729}.
FT   DOMAIN          118..234
FT                   /note="Heparin-sulfate lyase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16889"
SQ   SEQUENCE   524 AA;  56688 MW;  AA2C40F63E7FF9FD CRC64;
     MRGARQWVAR LATLRGGHVP DAPSVALRDP WPGEPARGAR IIKGEIEYQN VVRPLRPGLF
     HENDGSPVFI AHIQGFSWLR DLRALGTDAA RTRARALIAD WIRCETLPPL AEAPEVAGAR
     IAAWLGHYDF FAASADDDFR QMLMSRLVAE ARMLSANLPA EARDARAFTA IKGLIAAAVA
     LPEHGGFMQR ALRFLVPELE RQILPDGSHV ERSPSVHFSV LQDLAEIRAL LQLARAEVPP
     QLPGAIERLA IGLRALRHGD GGLALFNGTS EDWPNLIDLV LSQAGRTGRS ALALAGAGFH
     RLAAGRSLVI VDAGQPPGPG TDRFAHAGTL SFEFSVGRDR LIVNCGAAPA ASSGWRDALR
     NTAAHSTVVV ADVSSSELID QGLGRRPAHV EVQRQEANGA HWIEASHDGW QKVLGVVHRR
     RLYLAESGDD LRGEDSIEAD QPQPFTLRFH LHPNVTASIQ QDGEGALLRL ASGQGWRLRA
     GGATMSIEES IYFGGPEPRR AEQIVLTGTP DGPQQVKWAL TRMG
//