ID A0A258NTM8_9BURK Unreviewed; 492 AA.
AC A0A258NTM8;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 15.
DE SubName: Full=Succinate-semialdehyde dehydrogenase (NADP(+)) {ECO:0000313|EMBL:OYY33665.1};
GN Name=gabD {ECO:0000313|EMBL:OYY33665.1};
GN ORFNames=B7Y60_18685 {ECO:0000313|EMBL:OYY33665.1};
OS Polaromonas sp. 35-63-35.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Comamonadaceae; Polaromonas.
OX NCBI_TaxID=1970418 {ECO:0000313|EMBL:OYY33665.1, ECO:0000313|Proteomes:UP000216365};
RN [1] {ECO:0000313|EMBL:OYY33665.1, ECO:0000313|Proteomes:UP000216365}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=35-63-35 {ECO:0000313|EMBL:OYY33665.1};
RA Kantor R.S., Colenbrander Nelson T., Marshall S., Bennett D., Apte S.,
RA Camacho D., Thomas B.C., Warren L.A., Banfield J.F.;
RT "Lifting the veil on microbial sulfur biogeochemistry in mining
RT wastewaters.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYY33665.1}.
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DR EMBL; NCFQ01000016; OYY33665.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A258NTM8; -.
DR Proteomes; UP000216365; Unassembled WGS sequence.
DR GO; GO:0009013; F:succinate-semialdehyde dehydrogenase [NAD(P)+] activity; IEA:InterPro.
DR GO; GO:0009450; P:gamma-aminobutyric acid catabolic process; IEA:InterPro.
DR CDD; cd07103; ALDH_F5_SSADH_GabD; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR010102; Succ_semiAld_DH.
DR NCBIfam; TIGR01780; SSADH; 1.
DR PANTHER; PTHR43353; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43353:SF5; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345}.
FT DOMAIN 27..484
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 264
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 492 AA; 52866 MW; 8DDA08520B4C6BF3 CRC64;
MDMKTSPISL LKDPSLFKTD ALINGQWVKG SSRFDVNDPS TGLKLADVAN LGAKEAEAAI
AAANAAWPAW RSKTGKERHA ILLKWYQLLM ANVEDLGRIM TAEQGKPFTE AKGEVTYGAS
FVEWFAEEAK RVNGETLPQF DNNRRLMVLK QPIGVCAAIT PWNFPLAMIT RKVAPALAAG
CPVVIKPAEL TPLTALAAAE LAVRAGVPAG VLNVLTADSD NSIAAGKVFC ASDVVRHISF
TGSTEVGRIL MAQSAPSIKK LSLELGGNAP FIVFDDADID SAVDGAMASK YRNAGQTCVC
ANRIYVQDGV YDKFVEKFAA KVKLLKVGNG FEEGVVQGPL IEDAAVEKVQ RHVDDAIARG
GKLMAGGKKL KGQFFEPTVI SEATGDMLCA KEETFGPFAP VFRFKHEQEA IDAANNTEFG
LASYFYSRDI GRIYRVAEAL EYGMVGINAG VIATEHVPFG GVKQSGLGRE GSSHGMEEYL
EMKYLCLGDI LK
//
