ID A0A258TQL1_9PROT Unreviewed; 969 AA.
AC A0A258TQL1;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Formate dehydrogenase {ECO:0000313|EMBL:OYY93741.1};
GN ORFNames=B7Y41_09715 {ECO:0000313|EMBL:OYY93741.1};
OS Hydrogenophilales bacterium 28-61-23.
OC Bacteria; Pseudomonadota; Hydrogenophilia; Hydrogenophilales.
OX NCBI_TaxID=1970530 {ECO:0000313|EMBL:OYY93741.1, ECO:0000313|Proteomes:UP000215898};
RN [1] {ECO:0000313|EMBL:OYY93741.1, ECO:0000313|Proteomes:UP000215898}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=28-61-23 {ECO:0000313|EMBL:OYY93741.1};
RA Kantor R.S., Colenbrander Nelson T., Marshall S., Bennett D., Apte S.,
RA Camacho D., Thomas B.C., Warren L.A., Banfield J.F.;
RT "Lifting the veil on microbial sulfur biogeochemistry in mining
RT wastewaters.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OYY93741.1}.
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DR EMBL; NCGJ01000008; OYY93741.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A258TQL1; -.
DR Proteomes; UP000215898; Unassembled WGS sequence.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd02783; MopB_CT_2; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 2.
DR Gene3D; 2.20.25.90; ADC-like domains; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR InterPro; IPR006963; Mopterin_OxRdtase_4Fe-4S_dom.
DR InterPro; IPR006655; Mopterin_OxRdtase_prok_CS.
DR PANTHER; PTHR43598:SF5; DMSO REDUCTASE CHAIN A; 1.
DR PANTHER; PTHR43598; TUNGSTEN-CONTAINING FORMYLMETHANOFURAN DEHYDROGENASE 2 SUBUNIT B; 1.
DR Pfam; PF04879; Molybdop_Fe4S4; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SMART; SM00926; Molybdop_Fe4S4; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
DR PROSITE; PS51669; 4FE4S_MOW_BIS_MGD; 1.
DR PROSITE; PS00932; MOLYBDOPTERIN_PROK_3; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT DOMAIN 17..73
FT /note="4Fe-4S Mo/W bis-MGD-type"
FT /evidence="ECO:0000259|PROSITE:PS51669"
SQ SEQUENCE 969 AA; 108663 MW; AD2773143E256946 CRC64;
MTQTLTASKS EPAALHEEVR TTTCYMCACR CGIKVHLKNG EVRFIEGNID HPLNQGVLCA
KGSSGIMKQY SPARLTRPLR RKAGADRGVG EFEPISWDEA FAILEERLGK IRATDPKKFA
LFTGRDQMQA LTGLFARQFG TPNYAAHGGF CSVNMAAGLI YTIGGSFWEF GGPDLDRAKL
FVMLGTAEDH HSNPMKIALS KFKRDGGRFI SINPVRTGYS AIADEWIPIK PGTDGALLLA
LIHEIIKQGL YDREFLVQYS NSAELVNIDA KSHEEGMFVR FEVPPEEGCF DPQNKLWWDR
EMDRPVGTHT PGVDPYLLGE FKLADGTPVK PAFQLLAERV EQYTPEWAAG ITGIPVETIR
RLAHEMGVTA RDQKIELPIA WTDVWDNEHK TITGNPVAFH AMRGLAAHSN GFHGIRALGI
LMSLLGTIDR PGGFRHKAPF PRPIPPCAKT PTTPEAVRPN TPLDGMPLGW PADPDDLFVD
DDGGPVRIDK AFSWEYPLSV HGLMHNVITN AWRGDPYKID TLLIFMANMA WNSTMNAVEV
RKMLNDKEED GSYKIPFIVV ADAFQSEMTA FADLILPDTT YLERHDAMSM LDRPISEFDG
PVDSVRIPVL PPTGECKPFQ EVLIELGSRL KLPAFTTKEG NRKFRDYPDF IVNFETAPGS
GIGFLAGWRG KGGEKSMKGE PNPNQWQMYE QNNCVFQYHL PKSYQYMRNW NQGYLQWAQA
HGMTRHSEPI NIHIYSEVLQ KFRLAAQGKT DGRQPPAHLK KRIETYFDPL PFYYEPLEAT
LSDKHKYPLN AVTQRPMAMY HSWDSQNAWL RQIHAYNYLH INPKTAAAQG IADDDWIWIE
SMHGKVRCMA RLSEAVEPGT VWTWNAIGKA AGAWNLDKDA NESKQGFLLN HLISEELPRN
EAGEHISNSD PVTGQAAWYD VRVRIYKAGA DEPKETWPQF TAVPAAPGTP GRRPWQNYVA
GLFGKGEGK
//
