ID A0A259E6P9_9PROT Unreviewed; 437 AA.
AC A0A259E6P9;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Integrase {ECO:0008006|Google:ProtNLM};
GN ORFNames=B7X93_13360 {ECO:0000313|EMBL:OZA21919.1};
OS Hydrogenophilales bacterium 17-61-9.
OC Bacteria; Pseudomonadota; Hydrogenophilia; Hydrogenophilales.
OX NCBI_TaxID=1970524 {ECO:0000313|EMBL:OZA21919.1, ECO:0000313|Proteomes:UP000215711};
RN [1] {ECO:0000313|EMBL:OZA21919.1, ECO:0000313|Proteomes:UP000215711}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17-61-9 {ECO:0000313|EMBL:OZA21919.1};
RA Kantor R.S., Colenbrander Nelson T., Marshall S., Bennett D., Apte S.,
RA Camacho D., Thomas B.C., Warren L.A., Banfield J.F.;
RT "Lifting the veil on microbial sulfur biogeochemistry in mining
RT wastewaters.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the 'phage' integrase family.
CC {ECO:0000256|ARBA:ARBA00008857}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OZA21919.1}.
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DR EMBL; NCIF01000216; OZA21919.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A259E6P9; -.
DR Proteomes; UP000215711; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0075713; P:establishment of integrated proviral latency; IEA:UniProtKB-KW.
DR GO; GO:0046718; P:viral entry into host cell; IEA:UniProtKB-KW.
DR GO; GO:0044826; P:viral genome integration into host DNA; IEA:UniProtKB-KW.
DR CDD; cd00801; INT_P4_C; 1.
DR Gene3D; 1.10.150.130; -; 1.
DR Gene3D; 3.30.160.390; Integrase, DNA-binding domain; 1.
DR Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR InterPro; IPR044068; CB.
DR InterPro; IPR011010; DNA_brk_join_enz.
DR InterPro; IPR013762; Integrase-like_cat_sf.
DR InterPro; IPR002104; Integrase_catalytic.
DR InterPro; IPR038488; Integrase_DNA-bd_sf.
DR InterPro; IPR025166; Integrase_DNA_bind_dom.
DR InterPro; IPR010998; Integrase_recombinase_N.
DR InterPro; IPR004107; Integrase_SAM-like_N.
DR PANTHER; PTHR30629; PROPHAGE INTEGRASE; 1.
DR PANTHER; PTHR30629:SF2; PROPHAGE INTEGRASE INTS-RELATED; 1.
DR Pfam; PF13356; Arm-DNA-bind_3; 1.
DR Pfam; PF14659; Phage_int_SAM_3; 1.
DR Pfam; PF00589; Phage_integrase; 1.
DR SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR PROSITE; PS51900; CB; 1.
DR PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE 3: Inferred from homology;
KW DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01248};
KW Viral genome integration {ECO:0000256|ARBA:ARBA00023195};
KW Virus entry into host cell {ECO:0000256|ARBA:ARBA00023296}.
FT DOMAIN 101..181
FT /note="Core-binding (CB)"
FT /evidence="ECO:0000259|PROSITE:PS51900"
FT DOMAIN 203..383
FT /note="Tyr recombinase"
FT /evidence="ECO:0000259|PROSITE:PS51898"
SQ SEQUENCE 437 AA; 49245 MW; CEBE158ABDAB9E87 CRC64;
MLSSLKVKTA KPETRAYKLA DSGGLYLLVQ PNGSKLWRYK FRVNGTEGLQ ALGTFPEISL
ADARGLHADA RKLVAHGINP TQARRDKEIV QAQKQLARVN GSFATVMSDW NAATAGDLRP
STVKQRKREI DNDLLPKFKG RQIGEITRLE LTALLKSVEQ RAPEVARNLR NYLWGVFEYA
IDSGLIENNP VPPVRVLKKR KQKNHPALSD RQIGVFLGAL DDATKINEET RIAMLLVLLT
VCRKAEVIEA RWNEIDLEGA QWEIPAARMK AKRTHWVPLP PQAVALLTRL RALVPADREH
LFPNRVDPHR PMANRSLNAL MERLGFSGEG TPHGMRASFS TYFNSIGGNI DVIEHCLAHA
PTNAVRAAYN RHVYQNERRA MLQQWADYLD RLREEQASSR HESFTPADKT AEKLNLLNLT
DRFAVVPECQ NADAIRE
//
