ID A0A259EEA9_9PROT Unreviewed; 605 AA.
AC A0A259EEA9;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=UvrABC system protein B {ECO:0000256|ARBA:ARBA00029504};
DE Flags: Fragment;
GN ORFNames=B7X93_11305 {ECO:0000313|EMBL:OZA24643.1};
OS Hydrogenophilales bacterium 17-61-9.
OC Bacteria; Pseudomonadota; Hydrogenophilia; Hydrogenophilales.
OX NCBI_TaxID=1970524 {ECO:0000313|EMBL:OZA24643.1, ECO:0000313|Proteomes:UP000215711};
RN [1] {ECO:0000313|EMBL:OZA24643.1, ECO:0000313|Proteomes:UP000215711}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17-61-9 {ECO:0000313|EMBL:OZA24643.1};
RA Kantor R.S., Colenbrander Nelson T., Marshall S., Bennett D., Apte S.,
RA Camacho D., Thomas B.C., Warren L.A., Banfield J.F.;
RT "Lifting the veil on microbial sulfur biogeochemistry in mining
RT wastewaters.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Forms a heterotetramer with UvrA during the search for
CC lesions. Interacts with UvrC in an incision complex.
CC {ECO:0000256|ARBA:ARBA00026033}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the UvrB family.
CC {ECO:0000256|ARBA:ARBA00008533}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OZA24643.1}.
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DR EMBL; NCIF01000142; OZA24643.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A259EEA9; -.
DR Proteomes; UP000215711; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR CDD; cd18790; SF2_C_UvrB; 1.
DR Gene3D; 6.10.140.240; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR Gene3D; 4.10.860.10; UVR domain; 1.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001943; UVR_dom.
DR InterPro; IPR036876; UVR_dom_sf.
DR InterPro; IPR004807; UvrB.
DR InterPro; IPR041471; UvrB_inter.
DR InterPro; IPR024759; UvrB_YAD/RRR_dom.
DR NCBIfam; TIGR00631; uvrb; 1.
DR PANTHER; PTHR24029; UVRABC SYSTEM PROTEIN B; 1.
DR PANTHER; PTHR24029:SF0; UVRABC SYSTEM PROTEIN B; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF02151; UVR; 1.
DR Pfam; PF12344; UvrB; 1.
DR Pfam; PF17757; UvrB_inter; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF46600; C-terminal UvrC-binding domain of UvrB; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50151; UVR; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW SOS response {ECO:0000256|ARBA:ARBA00023236}.
FT DOMAIN 1..95
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 365..518
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT DOMAIN 562..597
FT /note="UVR"
FT /evidence="ECO:0000259|PROSITE:PS50151"
FT COILED 558..604
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:OZA24643.1"
SQ SEQUENCE 605 AA; 69646 MW; 85A560D527F3554C CRC64;
NKTLAAQLYS EMREFFPENA VEYFVSYYDY YQPEAYVPAR DLFIEKDSSI NEHIEQMRLS
ATKSLLERRD TIIVCTVSAI YGIGDPSDYH SMILLLRENE KMTQRDVITR LTQMQYDRND
IEFKRGVFRV RGDVIDIFPA EHAETAIRVE LFDDVVETLH LFDPLTGQIL SKVARFTVFP
SSHYVTPRAT ILRAIEAIKI ELRERLEWYY ANGKLVEAQR LEQRTRFDLE MMGELGFCKG
IENYSRHLSG RKPGEPPPTL IDYLAKDALM FIDESHVTVT QVGGMYKGDR SRKENLVDYG
FRMPSALDNR PLKFEEFEGL MPQTVFVSAT PAKYETEHAG QVVEQLVRPT GLVDPVIEVR
PVGTQVDDLM SEARKRIAIG ERVLVTTLTK RMSEDLTDYL TEHGIKVRYL HSDIDTVERV
EIIRDLRLGV FDVLVGINLL REGLDIPEVS LVTILDADKE GFLRSERALI QTIGRAARHL
NGMAILYADK ITHSMQRAME ETERRRIKQT AFNLEHGITP RGVTKRIKDI IDGVYDADAS
RQELKAAQIV AEYKVLDEKT LTKRIKKLEK DMLDAAKNLE FEKAAELRDQ LRQLKQVLFG
VEEHD
//
