ID A0A259FGC0_9PROT Unreviewed; 681 AA.
AC A0A259FGC0;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 14.
DE RecName: Full=Flagellar biosynthesis protein FlhA {ECO:0000256|RuleBase:RU364093};
GN Name=flhA {ECO:0000256|RuleBase:RU364093};
GN ORFNames=B7X87_10735 {ECO:0000313|EMBL:OZA37643.1};
OS Hydrogenophilales bacterium 17-64-34.
OC Bacteria; Pseudomonadota; Hydrogenophilia; Hydrogenophilales.
OX NCBI_TaxID=1970527 {ECO:0000313|EMBL:OZA37643.1, ECO:0000313|Proteomes:UP000216129};
RN [1] {ECO:0000313|EMBL:OZA37643.1, ECO:0000313|Proteomes:UP000216129}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=17-64-34 {ECO:0000313|EMBL:OZA37643.1};
RA Kantor R.S., Colenbrander Nelson T., Marshall S., Bennett D., Apte S.,
RA Camacho D., Thomas B.C., Warren L.A., Banfield J.F.;
RT "Lifting the veil on microbial sulfur biogeochemistry in mining
RT wastewaters.";
RL Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for formation of the rod structure of the flagellar
CC apparatus. Together with FliI and FliH, may constitute the export
CC apparatus of flagellin. {ECO:0000256|RuleBase:RU364093}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU364093};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU364093}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the FHIPEP (flagella/HR/invasion proteins export
CC pore) family. {ECO:0000256|ARBA:ARBA00008835,
CC ECO:0000256|RuleBase:RU364093}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU364093}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OZA37643.1}.
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DR EMBL; NCIL01000008; OZA37643.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A259FGC0; -.
DR Proteomes; UP000216129; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0044780; P:bacterial-type flagellum assembly; IEA:InterPro.
DR GO; GO:0009306; P:protein secretion; IEA:InterPro.
DR Gene3D; 3.40.30.60; FHIPEP family, domain 1; 1.
DR Gene3D; 1.10.8.540; FHIPEP family, domain 3; 1.
DR Gene3D; 3.40.50.12790; FHIPEP family, domain 4; 1.
DR InterPro; IPR042194; FHIPEP_1.
DR InterPro; IPR042193; FHIPEP_3.
DR InterPro; IPR042196; FHIPEP_4.
DR InterPro; IPR006301; FlhA.
DR InterPro; IPR001712; T3SS_FHIPEP.
DR NCBIfam; TIGR01398; FlhA; 1.
DR PANTHER; PTHR30161:SF1; FLAGELLAR BIOSYNTHESIS PROTEIN FLHA-RELATED; 1.
DR PANTHER; PTHR30161; FLAGELLAR EXPORT PROTEIN, MEMBRANE FLHA SUBUNIT-RELATED; 1.
DR Pfam; PF00771; FHIPEP; 1.
DR PIRSF; PIRSF005419; FlhA; 1.
DR PRINTS; PR00949; TYPE3IMAPROT.
PE 3: Inferred from homology;
KW Bacterial flagellum biogenesis {ECO:0000256|RuleBase:RU364093};
KW Bacterial flagellum protein export {ECO:0000256|RuleBase:RU364093};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU364093};
KW Cell projection {ECO:0000313|EMBL:OZA37643.1};
KW Cilium {ECO:0000313|EMBL:OZA37643.1};
KW Flagellum {ECO:0000313|EMBL:OZA37643.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU364093};
KW Protein transport {ECO:0000256|RuleBase:RU364093};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU364093};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU364093}; Transport {ECO:0000256|RuleBase:RU364093}.
FT TRANSMEM 32..49
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 61..81
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 101..124
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 194..215
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 235..257
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
FT TRANSMEM 269..289
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU364093"
SQ SEQUENCE 681 AA; 72742 MW; 097B40BFB2A498B7 CRC64;
MPFNRLAVPL LVLLILAMMV LPLPTFMLDV LFTLNIALAM IVLLVSLNAR RPLDFSVFPT
VLLLTTLLRL SLNVASTRII LMQGHTGPDA AGKVIESFGN FLVGGNIAVG LVVFLILVII
NFVVITKGAG RIAEVAARFT LDSMPGKQLA VDADLQAGFI NEGEARSRRA DIGREADFYG
AMDGASKFVR GDAVAGLIIL LVNLVGGVAV GLLQHDLGVS EALGRYALLT VGDGLVTQIP
ALIISTAAGI VVSRASSEQD LSREFSTQVF GRPQTLFVAA AVLGVLGLIP GTPHLAFLSI
AVVLAGLGGW IGRRRPAVRD VELLDEEDVV PTPVDVTWDD IPPVDVLALE VGYRLIPLVD
RNQGGAALAR ITEARRRFAA DMGLVVPLIR VRDNLDLKPN IYRITLKGVD VAHGDMPNGH
ALAVDMGEVL GRLDGAPGVD PLTGLAGVWI EAGREEEAEL RGFVVLQPQD VIARQVEAVF
RQHAPELLGR TEVQQLLDTL SRTHPGLVED VTPRHLPLTT VQAILQQLIA ENVSIRDTRT
LFETLAARAA KTQAVDELVE TVRAALGRSI VDRLFEGSDT LNVMGLSAAT ESRLLAEMGD
EGEALLSPAT LDALNEAAER ALAEQQAEGH PPVLLTSPGL RAILSRLLRR NLPRLSVLAY
AEVPADKMVR MTSELAIEAG A
//
