ID A0A259UBX1_9FIRM Unreviewed; 790 AA.
AC A0A259UBX1;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Formate dehydrogenase subunit alpha {ECO:0000313|EMBL:OZC15468.1};
DE EC=1.2.1.2 {ECO:0000313|EMBL:OZC15468.1};
GN Name=fdhA_1 {ECO:0000313|EMBL:OZC15468.1};
GN ORFNames=SPSIL_41690 {ECO:0000313|EMBL:OZC15468.1};
OS Sporomusa silvacetica DSM 10669.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Sporomusaceae;
OC Sporomusa.
OX NCBI_TaxID=1123289 {ECO:0000313|EMBL:OZC15468.1, ECO:0000313|Proteomes:UP000216752};
RN [1] {ECO:0000313|EMBL:OZC15468.1, ECO:0000313|Proteomes:UP000216752}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 10669 {ECO:0000313|EMBL:OZC15468.1,
RC ECO:0000313|Proteomes:UP000216752};
RA Poehlein A., Daniel R.;
RT "Genome sequence of Sporomusa silvacetica DSM 10669.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OZC15468.1}.
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DR EMBL; LSLK01000100; OZC15468.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A259UBX1; -.
DR Proteomes; UP000216752; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR CDD; cd02792; MopB_CT_Formate-Dh-Na-like; 1.
DR Gene3D; 2.40.40.20; -; 1.
DR Gene3D; 3.40.50.740; -; 1.
DR Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 2.
DR InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR InterPro; IPR006656; Mopterin_OxRdtase.
DR PANTHER; PTHR43598:SF1; FORMATE DEHYDROGENASE, NITRATE-INDUCIBLE, MAJOR SUBUNIT; 1.
DR PANTHER; PTHR43598; TUNGSTEN-CONTAINING FORMYLMETHANOFURAN DEHYDROGENASE 2 SUBUNIT B; 1.
DR Pfam; PF00384; Molybdopterin; 1.
DR Pfam; PF01568; Molydop_binding; 1.
DR SUPFAM; SSF50692; ADC-like; 1.
DR SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:OZC15468.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000216752}.
FT DOMAIN 2..418
FT /note="Molybdopterin oxidoreductase"
FT /evidence="ECO:0000259|Pfam:PF00384"
FT DOMAIN 667..781
FT /note="Molybdopterin dinucleotide-binding"
FT /evidence="ECO:0000259|Pfam:PF01568"
SQ SEQUENCE 790 AA; 86459 MW; 8F85673F6CE4D6B3 CRC64;
MENSRWFLIA GSNAAENHPI AMKYLLRAQE KGAKIIVVDP RFTRTAAKAN LFAQIRPGTD
IAYLGAIINY ILQNSLYNKE YLVNFTNALC KINPAYEFQD GLFSGYDSTK GSYATDSWSY
VLDEQGQPVK AASVEEPGTV FSLMKQHYSR YTLEIGSAIS GIPAETIKQI ADIITKNGIG
TIMYALGMTQ HTTATQGIRC YAIIQLLLGN IGVAGGGVNA LRGEPNVQGS TDFSNLSTTL
PGYLPTPMEE DKDAATYGMK YGLTNLKHLI SLQKAWYGEN ATADNDYAYG YLPRITTGKA
TSYIPMTEDM SRGQFKLLLN VGINPRVSIP NNAVVQSGLA KLEMMVVSDF FETETASFWK
APGVNSDEIK TEVIFLPVAF SYEKAGSLTN SGRWIQWKSA ALKPEGSCRA DLDIFDSIFR
KVRSLYAGST DPKDAPILHS VWDYGHEADP EKVLQEINGY NMTTGKLLGS LGEYLAGEAG
QVSSGCWIYS GVYGNGNLAK RRDGKDPGGL GLFPQWTYAW PANIRILYNR ASCNQQGQPL
DATRQLVWWD LAKSQWVGND VPDVPDRSKG PDTPQGKTAF RMNADQMARL FTAPFKNMKP
GTNLPTSLAG INSDGPLPEF YEPIESPTSN VLHPNVQSNP LAKVRQAIKE KQQLGGKEEF
PFVLTTYTSG TEHFCSGSLT RNLPWLVEFM PEPFLEMGKA MASKLGVTNG EVVELSSARG
ILQVKAMVTN RIQPLMINGK ETYTVGMPFG WGYAGLGTGP SVNNLTHAAF DPAAGTPEFK
AQLVNVRKVK
//
