ID   A0A259UDK2_9FIRM        Unreviewed;       369 AA.
AC   A0A259UDK2;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=Uroporphyrinogen decarboxylase {ECO:0000313|EMBL:OZC16205.1};
DE            EC=4.1.1.37 {ECO:0000313|EMBL:OZC16205.1};
GN   Name=hemE_13 {ECO:0000313|EMBL:OZC16205.1};
GN   ORFNames=SPACI_45720 {ECO:0000313|EMBL:OZC16205.1};
OS   Sporomusa acidovorans DSM 3132.
OC   Bacteria; Bacillota; Negativicutes; Selenomonadales; Sporomusaceae;
OC   Sporomusa.
OX   NCBI_TaxID=1123286 {ECO:0000313|EMBL:OZC16205.1, ECO:0000313|Proteomes:UP000216052};
RN   [1] {ECO:0000313|EMBL:OZC16205.1, ECO:0000313|Proteomes:UP000216052}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 3132 {ECO:0000313|EMBL:OZC16205.1,
RC   ECO:0000313|Proteomes:UP000216052};
RA   Poehlein A., Daniel R.;
RT   "Genome sequence of Sporomusa acidovorans DSM 3132.";
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OZC16205.1}.
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DR   EMBL; LSLL01000094; OZC16205.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A259UDK2; -.
DR   STRING; 112900.SAMN04488499_101172; -.
DR   Proteomes; UP000216052; Unassembled WGS sequence.
DR   GO; GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:InterPro.
DR   Gene3D; 3.20.20.210; -; 1.
DR   InterPro; IPR038071; UROD/MetE-like_sf.
DR   InterPro; IPR000257; Uroporphyrinogen_deCOase.
DR   PANTHER; PTHR47099; METHYLCOBAMIDE:COM METHYLTRANSFERASE MTBA; 1.
DR   PANTHER; PTHR47099:SF1; METHYLCOBAMIDE:COM METHYLTRANSFERASE MTBA; 1.
DR   Pfam; PF01208; URO-D; 1.
DR   SUPFAM; SSF51726; UROD/MetE-like; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000313|EMBL:OZC16205.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000216052}.
FT   DOMAIN          180..366
FT                   /note="Uroporphyrinogen decarboxylase (URO-D)"
FT                   /evidence="ECO:0000259|Pfam:PF01208"
SQ   SEQUENCE   369 AA;  41466 MW;  4C0A843A96342358 CRC64;
     MMKTPQELLQ ERKERLKKTI AFEQTDRTPV IIAGDAVFAR HVGMKLSEFV SNMKASHQAI
     LSSFKDLGDV DGTGSTYATA TIFPLIFYSK VKLPGRELPD NTPWQLDERE LMTVADYDTI
     LNKGWKAFSD DYLKNRVGFD LDSIREQLKD VPNFIKDFED AGIVVYSPKA SSTVNEFLGG
     GRSFPKFMRD MFKMPDKVEA VLDVILEENL AELRQQIRAI KPMVVFMSPA RGASEFYSPK
     IWQRFVWKYL KAAAEAIIEE GAIADLHIDG NWERDLEFFK TLPKHKCIFE SDGATNIYKV
     REVLGDHMCI KGDVPAAMLA LGTPDDVYNY STKLIKDMGK GFILASGCTI PPNAKFENVK
     AMVAAASGK
//