ID A0A259UIV2_9FIRM Unreviewed; 472 AA.
AC A0A259UIV2;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=2-iminoacetate synthase {ECO:0000313|EMBL:OZC18025.1};
DE EC=4.1.99.19 {ECO:0000313|EMBL:OZC18025.1};
GN Name=thiH_1 {ECO:0000313|EMBL:OZC18025.1};
GN ORFNames=SPSIL_28240 {ECO:0000313|EMBL:OZC18025.1};
OS Sporomusa silvacetica DSM 10669.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Sporomusaceae;
OC Sporomusa.
OX NCBI_TaxID=1123289 {ECO:0000313|EMBL:OZC18025.1, ECO:0000313|Proteomes:UP000216752};
RN [1] {ECO:0000313|EMBL:OZC18025.1, ECO:0000313|Proteomes:UP000216752}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 10669 {ECO:0000313|EMBL:OZC18025.1,
RC ECO:0000313|Proteomes:UP000216752};
RA Poehlein A., Daniel R.;
RT "Genome sequence of Sporomusa silvacetica DSM 10669.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OZC18025.1}.
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DR EMBL; LSLK01000073; OZC18025.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A259UIV2; -.
DR OrthoDB; 9801120at2; -.
DR Proteomes; UP000216752; Unassembled WGS sequence.
DR GO; GO:0036355; F:2-iminoacetate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR010722; BATS_dom.
DR InterPro; IPR024007; FeFe-hyd_mat_HydG.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR034428; ThiH/NoCL/HydG-like.
DR NCBIfam; TIGR03955; rSAM_HydG; 1.
DR PANTHER; PTHR43583; 2-IMINOACETATE SYNTHASE; 1.
DR PANTHER; PTHR43583:SF2; BIOTIN AND THIAMIN SYNTHESIS ASSOCIATED DOMAIN CONTAINING PROTEIN; 1.
DR Pfam; PF06968; BATS; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01081; cleavage_of_the_Ca-Cb_bond_in; 1.
DR SFLD; SFLDF00319; Fe_hydrogenase_maturase_(HydG; 1.
DR SMART; SM00876; BATS; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Lyase {ECO:0000313|EMBL:OZC18025.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000216752};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 82..320
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 472 AA; 53326 MW; FC82DA061A03A439 CRC64;
MYNCKSKIAT EFIDDQEVLD TLAFAQQNKS NRELIDSLIE RARDCKGLTH REAAVLLECD
LEDENEKMMS LAKEIKQKLY GNRIVMFAPL YLSNYCINGC VYCPYHFKNK NISRKKLSQE
DIAREVTALQ DMGHKRLALE TGEDPVNNPI EYVLESIKTI YSIKHKNGAI RRVNVNIAAT
TVENYRKLKD AGIGTYILFQ ETYNKKAYEE LHPTGPKKDY AYHTEAMDRA MEGGIDDVGV
GVLFGLNMYR YDFVGLLMHA EHLEAAMGVG PHTISVPRIR PADDIDPENF SNAISDDIFA
KIVTVLRIAV PYTGMIVSTR ESQKTRERVL ELGISQVSGA SSTSVGGYYE KEAEDDNSAQ
FDVNDSRTLD EVVNWLLTLG YIPSFCTACY REGRTGDRFM SLVKTGQIAN CCQPNALMTL
KEYLEDYASA DTKAKGETVI ANEIPRITNE KVRKIAIEHL TELNDGKRDF RF
//
