ID A0A259URH3_9FIRM Unreviewed; 388 AA.
AC A0A259URH3;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE RecName: Full=UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) {ECO:0000256|ARBA:ARBA00038858};
DE EC=5.1.3.14 {ECO:0000256|ARBA:ARBA00038858};
GN Name=mnaA {ECO:0000313|EMBL:OZC20632.1};
GN ORFNames=SPSIL_15000 {ECO:0000313|EMBL:OZC20632.1};
OS Sporomusa silvacetica DSM 10669.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Sporomusaceae;
OC Sporomusa.
OX NCBI_TaxID=1123289 {ECO:0000313|EMBL:OZC20632.1, ECO:0000313|Proteomes:UP000216752};
RN [1] {ECO:0000313|EMBL:OZC20632.1, ECO:0000313|Proteomes:UP000216752}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 10669 {ECO:0000313|EMBL:OZC20632.1,
RC ECO:0000313|Proteomes:UP000216752};
RA Poehlein A., Daniel R.;
RT "Genome sequence of Sporomusa silvacetica DSM 10669.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-
CC mannosamine; Xref=Rhea:RHEA:17213, ChEBI:CHEBI:57705,
CC ChEBI:CHEBI:68623; EC=5.1.3.14;
CC Evidence={ECO:0000256|ARBA:ARBA00036080};
CC -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC {ECO:0000256|ARBA:ARBA00038209, ECO:0000256|RuleBase:RU003513}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OZC20632.1}.
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DR EMBL; LSLK01000059; OZC20632.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A259URH3; -.
DR OrthoDB; 9803238at2; -.
DR Proteomes; UP000216752; Unassembled WGS sequence.
DR GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:UniProtKB-EC.
DR CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR InterPro; IPR029767; WecB-like.
DR NCBIfam; TIGR00236; wecB; 1.
DR PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR PANTHER; PTHR43174:SF2; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR Pfam; PF02350; Epimerase_2; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU003513};
KW Reference proteome {ECO:0000313|Proteomes:UP000216752}.
FT DOMAIN 32..368
FT /note="UDP-N-acetylglucosamine 2-epimerase"
FT /evidence="ECO:0000259|Pfam:PF02350"
SQ SEQUENCE 388 AA; 43322 MW; 6AA95660348701F8 CRC64;
MSRIKVMTVF GTRPEAIKMA PVVLELAKHP EYITPVVAVT AQHREMLDQV LGLFKITPNY
DLDIMSQGQT LFDITCRAMQ GLNQVLAEEK PDIVLVHGDT TTTFAGALAA FYHQIVIGHV
EAGLRTGDKY SPYPEEMNRK LTGTLTDIHF APTSTARQNL LQEKVDPKTV FVTGNTVIDA
LKATIDSTYR FIDPLLQSID YDSRKVILVT THRRENLGEP MRHVYQALKA IVDGFDDVEI
VFPVHKNPLV RQVVQEELGG LSHVHLIDPL DYQPFANLMA RSYLILTDSG GIQEEAPALG
KPVLVLRDTT ERPEAVISGT VKLIGTDKER VYNETRELLV NDKEYQRMAS AVNPYGDGKA
SSRIVNAILY RHNLISTLPN EFEASSKE
//
