ID A0A259V1M0_9FIRM Unreviewed; 358 AA.
AC A0A259V1M0;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 10.
DE SubName: Full=Homoisocitrate dehydrogenase {ECO:0000313|EMBL:OZC24138.1};
DE EC=1.1.1.87 {ECO:0000313|EMBL:OZC24138.1};
GN Name=hicd_2 {ECO:0000313|EMBL:OZC24138.1};
GN ORFNames=SPACI_01740 {ECO:0000313|EMBL:OZC24138.1};
OS Sporomusa acidovorans DSM 3132.
OC Bacteria; Bacillota; Negativicutes; Selenomonadales; Sporomusaceae;
OC Sporomusa.
OX NCBI_TaxID=1123286 {ECO:0000313|EMBL:OZC24138.1, ECO:0000313|Proteomes:UP000216052};
RN [1] {ECO:0000313|EMBL:OZC24138.1, ECO:0000313|Proteomes:UP000216052}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 3132 {ECO:0000313|EMBL:OZC24138.1,
RC ECO:0000313|Proteomes:UP000216052};
RA Poehlein A., Daniel R.;
RT "Genome sequence of Sporomusa acidovorans DSM 3132.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- COFACTOR:
CC Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC Evidence={ECO:0000256|ARBA:ARBA00001936};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OZC24138.1}.
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DR EMBL; LSLL01000011; OZC24138.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A259V1M0; -.
DR STRING; 112900.SAMN04488499_10463; -.
DR Proteomes; UP000216052; Unassembled WGS sequence.
DR GO; GO:0047046; F:homoisocitrate dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0000287; F:magnesium ion binding; IEA:InterPro.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR InterPro; IPR019818; IsoCit/isopropylmalate_DH_CS.
DR InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR PANTHER; PTHR43275; D-MALATE DEHYDROGENASE [DECARBOXYLATING]; 1.
DR PANTHER; PTHR43275:SF1; D-MALATE DEHYDROGENASE [DECARBOXYLATING]; 1.
DR Pfam; PF00180; Iso_dh; 1.
DR SMART; SM01329; Iso_dh; 1.
DR SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
DR PROSITE; PS00470; IDH_IMDH; 1.
PE 4: Predicted;
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Oxidoreductase {ECO:0000313|EMBL:OZC24138.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000216052}.
FT DOMAIN 5..351
FT /note="Isopropylmalate dehydrogenase-like"
FT /evidence="ECO:0000259|SMART:SM01329"
SQ SEQUENCE 358 AA; 39285 MW; 302AB30EBB9A801E CRC64;
MKTYKLGVLY GDGIGPEIVK STVDVFVAAE NHVGNVKFDY VELPMGWEGI KKYNDPVPEI
TKKELKACDG WLFGPHDSAA YPPEHLAKLN PSGEMRHYFD LYSNVRPNKA IPGAKSLVGN
DVDMVIFREN TEGFYPDRNM YKGIGEFMAS PDVAIVAGLF TKKAAERIAH SAFRLAMKRR
KKVTIVHKAN VIKLGYGLFR DTCREVGKLY PEVQVDDYHI DAMTAHLVRR AKDFDVIVTT
NMFGDILSDL VGELTGSLGL APSINTNDHQ AMAQAAHGSA PDIAGKNISN PVGMLLSGVM
LLDWMAERHN DPALEKMARI AENAIMKTLA NGICTPDLGG SASTTGFTES IVERVKQL
//
