ID A0A260B7H5_9NOCA Unreviewed; 648 AA.
AC A0A260B7H5;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Acetoacetate--CoA ligase {ECO:0000313|EMBL:OZC99288.1};
GN ORFNames=CH275_22615 {ECO:0000313|EMBL:OZC99288.1};
OS Rhodococcus sp. 06-235-1A.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=2022508 {ECO:0000313|EMBL:OZC99288.1, ECO:0000313|Proteomes:UP000215839};
RN [1] {ECO:0000313|EMBL:OZC99288.1, ECO:0000313|Proteomes:UP000215839}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=06-235-1A {ECO:0000313|EMBL:OZC99288.1,
RC ECO:0000313|Proteomes:UP000215839};
RA Savory E.A., Fuller S.L., Weisberg A.J., Thomas W.J., Gordon M.I.,
RA Stevens D.M., Creason A.L., Belcher M.S., Wiseman M., Putnam M.L.,
RA Grunwald N.J., Chang J.H.;
RT "Evolutionary transitions between beneficial and phytopathogenic
RT Rhodococcus challenge disease management.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OZC99288.1}.
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DR EMBL; NOYI01000024; OZC99288.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A260B7H5; -.
DR OrthoDB; 9803968at2; -.
DR Proteomes; UP000215839; Unassembled WGS sequence.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:OZC99288.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 36..89
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 96..462
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 528..601
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 648 AA; 69928 MW; 4B083A8909F0D470 CRC64;
MISALWTPTD ADVAEARVTE FARFVEQRHD VELPDYEALW RWSTIELESF WRAVWDFFEI
RAVSDPTTVL ESRTMPGAQW FPGTELNYVD QVIGHARPDR AAIVHAREDG STRIVTWDDM
IDQAGALAGT LADNGVRRGD RVVGYLPNIP EAVIAFLATA SLGAVWSACG QDYSASAARD
RLGQLEPTAL ITASGYQYGG QFRDKSGDVA ALVDALPTVR VVVTIGEPTG SARSWSDATA
ESRELTPAAV PFDHPLWVVF SSGTTGLPKG IVHGHGGVVL EHLKSVALQS DLGPEDVFFW
YTSPSWMMWN FQIAGLLTGA TIVCADGNPA FPMPDALWDI AGRLGVTYLG TSPGYVLACI
KAGTHPGADH DLSALRAVGI TGSAMPASSS IWLSENIGAH VPVFSISGGT DVVSAFAGGV
RTAPVWAGEL SVPFLGVALD AYDEDGEPVR GTVGELVVTE PMPSMPLYFW NDADGSRYRA
AYFDTYPGIW RHGDWITLTD RGSVVVHGRS DSTLNRNGIR MGSADIYQAV ESLDEVTEAL
VLGIELPDGQ YWMPLFVVVP DGLTDELHAR IESVIRTQAS PRHVPDDIVA TPAIPHTRTG
KKLEIPLKRL FQGAAAAGTL DASAVDDPAA LAWFVDRATE FQRVQRAR
//
