ID A0A260BP74_9NOCA Unreviewed; 1475 AA.
AC A0A260BP74;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Non-ribosomal peptide synthetase {ECO:0000313|EMBL:OZD05099.1};
GN ORFNames=CH275_12040 {ECO:0000313|EMBL:OZD05099.1};
OS Rhodococcus sp. 06-235-1A.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=2022508 {ECO:0000313|EMBL:OZD05099.1, ECO:0000313|Proteomes:UP000215839};
RN [1] {ECO:0000313|EMBL:OZD05099.1, ECO:0000313|Proteomes:UP000215839}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=06-235-1A {ECO:0000313|EMBL:OZD05099.1,
RC ECO:0000313|Proteomes:UP000215839};
RA Savory E.A., Fuller S.L., Weisberg A.J., Thomas W.J., Gordon M.I.,
RA Stevens D.M., Creason A.L., Belcher M.S., Wiseman M., Putnam M.L.,
RA Grunwald N.J., Chang J.H.;
RT "Evolutionary transitions between beneficial and phytopathogenic
RT Rhodococcus challenge disease management.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OZD05099.1}.
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DR EMBL; NOYI01000012; OZD05099.1; -; Genomic_DNA.
DR OrthoDB; 2472181at2; -.
DR UniPathway; UPA00011; -.
DR Proteomes; UP000215839; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0008610; P:lipid biosynthetic process; IEA:UniProt.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 2.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 1.
DR PANTHER; PTHR45527:SF1; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR45527; NONRIBOSOMAL PEPTIDE SYNTHETASE; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF00668; Condensation; 2.
DR Pfam; PF00550; PP-binding; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 4.
DR PROSITE; PS00455; AMP_BINDING; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553}.
FT DOMAIN 933..1008
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
SQ SEQUENCE 1475 AA; 156823 MW; F1313253B1A70E2A CRC64;
MFDDAIPVSS SQADIWLAQQ FMPDVPFSIA YFVDIVGAVD VDALVACGSR AHREFSSSTM
RVFEVDGTPM QRFVDAETEA VEILDFRGHD RPAERARQWM NDDCRTPLSI YGQLVRLRVL
RVEDDRVFWY TRAHHIALDG YASMKVLERA AALYAAVQDG VGPPRIDPTT PAALLAEDER
YRASARALRD RAHWESADLG YGAPWGRSAQ PASVPIVVGE DRSISPTARG HATSTVVIAA
FAAFHSRMND VDDVDLSLPV SARPTAVLRG AGSSLSHVVP LRLPGAGSAT VNNVIKSAEV
AIGAVLRHQR SRPPVSESGN ALRAGRFGPT INVMMFANTV AVGDFDGEIN ILTTGPVSDL
AVNIYPGRGG ARPRIDFEAN PAAYTPSDLA RRHERFLHFL DHFGESGCGD TAVADLDLFL
PGEPDAVPAS VGATVVERGS LNDVFSTAIK QHGNRIAIQD ADVSVTYAES AARVDTLASI
LRARGIGTED RVAVRIGRSV AGIVSFWAIA RVGAVYVPVD PNHPRERAQF VVRDSGAVLG
LCTGGGGEFG GVEWLDLDAV VAEGDLDDVV APTAPGHAAY VIYTSGSTGT PKGVVVTHGG
IAALVQQIGS SYHLDVESRV CHLASPGFDT AIVEVLAAAT AGAAVVIAPA GSYAGAELTE
LIAQQAITHL LITPSALATL DPAALSGVGT IIIGGEAAPQ DTVDLWSVGR RLLNAYGPTE
TTCSVTMTAP LTPGSADGIG RAMVGAVIHL LDCTLRPVPS GAVGEIYIET PGVARGYLGR
TADTAARFAA NPFGSNASRM FRSGDRARLR GDGTLEFLGR TDDQIKIRGN RVELGEVDAA
LRACPNVAAA SSALRRSHTG DLRIDGYVVA APHGHLLDTE RIRQDLTRRL PAHMVPSTLS
VLDEIPLTIN RKVDRGALPA PDLTTSMTGA RTEPAGATEE MVAAAFARVF GRGGIDCAAS
FFDLGGDSLA ATRVVSMVRA KAAVDIGVRD LAGAPSVQAL AACVDERRLT GRQQNSRPER
GTSAGVSAIP LAPQQRHIDR NAQLPLYNLP FTVTISGEFH SAAASQALAD LIDRHSTLRT
RYPDVDGVPA QVVEPDSARA VPNLDVVDFD DAAVVETLEH PFDVRTEFAI RARLFAVESD
HHVLACAVHH SAADGWSLGL LASDFVLAYR ARIAGSAPSW AELPLQYADY SVWAAERDVS
GDLDFWRAEL ADTPGSRDLP LDRPRTQDWN FSGARTSLRF DADATERMTD LAQRCGTNRF
TVLRAALLIL LAQTTEATDI VIGTPVAGRD DPRLEQLVGT FTNTVAIRTN IAAASTVEDV
VQSARASELL AFDHASVPFE DVVADLAADS VDGRHPIFQV ALSLDVFATQ TLTMGDVRFE
ITPRPIDIAK CDLHFHVTEH RDGEGKAGVE PAERPRGAIE AAVDIVYPTA LFDANTVVAL
GQRLEQIVHA MVAGPTSPWR DMTALEPSAQ LLHGV
//
