ID A0A261A533_9PELO Unreviewed; 1150 AA.
AC A0A261A533;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Amino acid permease/ SLC12A domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=FL83_20910 {ECO:0000313|EMBL:OZF93196.1};
OS Caenorhabditis latens.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=1503980 {ECO:0000313|EMBL:OZF93196.1, ECO:0000313|Proteomes:UP000216463};
RN [1] {ECO:0000313|EMBL:OZF93196.1, ECO:0000313|Proteomes:UP000216463}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PX534 {ECO:0000313|EMBL:OZF93196.1,
RC ECO:0000313|Proteomes:UP000216463};
RA Fierst J.L.;
RT "Caenorhabditis latens genome sequence.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OZF93196.1}.
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DR EMBL; NIPN01000272; OZF93196.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A261A533; -.
DR STRING; 1503980.A0A261A533; -.
DR Proteomes; UP000216463; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015377; F:chloride:monoatomic cation symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR InterPro; IPR018491; SLC12_C.
DR InterPro; IPR004842; SLC12A_fam.
DR PANTHER; PTHR11827:SF53; K+_CL-COTRANSPORTER; 1.
DR PANTHER; PTHR11827; SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS; 1.
DR Pfam; PF00324; AA_permease; 2.
DR Pfam; PF03522; SLC12; 3.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000216463};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 183..208
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 220..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 266..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..362
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 477..498
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 510..534
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 612..631
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 637..658
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 670..688
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 189..363
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
FT DOMAIN 475..752
FT /note="Amino acid permease/ SLC12A"
FT /evidence="ECO:0000259|Pfam:PF00324"
FT DOMAIN 771..890
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT DOMAIN 905..973
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT DOMAIN 1057..1148
FT /note="SLC12A transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03522"
FT REGION 1..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1005..1078
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1029..1053
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1061..1078
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:OZF93196.1"
SQ SEQUENCE 1150 AA; 126130 MW; 62A1E1F9883AF0EB CRC64;
MGDDSSQDNT GTPPSGGAPT AGNSQQPASA IRNKVDVPPG FGRRVSSVEV VKNAMPPTKK
ASVVIFETPD TPKAERRASS WWRNLVMDDD KTAAAQPEII ISPEQAGNGL EDRHRNISTA
SVGDRELYAW GSNKDAGGNH NLALFEEPSM PFFSSYLKAH ITPGPLERAQ SSSHGGHGAK
ADLGVLLGVY LPTIQHILGV TMFIRLFWLV GIAGLGQTFL LLFLCCFCTF LTCISISAVA
TNGVVESGGA YFMISRNLGP EFGSAVGILF YLANTVATSM YLVGGVEILL LYIFPGLTFG
GAEGQHDTSL FGTMTNSLRF YSTILLLIEF AIVAMGVKFV QMLAPVSLIC VILSILACYA
GGVTKTISPE SGQYVCMFNN RLLQSSSLSN DSFDLASICD YCDKNNTYLY DKLCGLKGCN
NTELEKGFQC INGFPGFMGG QTLLSNLGPN YLDKGEAYPG APADIKSDVY QDVRTTFFVL
LAIYFPAVTG IFTGANMSGD LKNPQASIPA GTIAANLTTS FIYFSLAFIF GGAIDGAVLR
DKNGQSVGGQ MVVALLSWPS PWVLLIGSFL STFGAALQCL CSAPRLLQAI AKDEVIPLLS
PFKKVTANNE PFLGLILTTI IAEIAILMGS MDTIAAVVDF FFLMCYAFVN IICTLHSLLG
APNWRPRFKY YHWFLSLLGA VLCFFIMFST HWDYAIVACL LCLVIYKYVE WKGAKKEWGD
GIRGLALTTA QYSLMKIEDK EPHPKNWRPQ LLLLLSMQWS KEIIDVRYLN LLNLASQLKA
GKGLTVVTAF LKGDPTSPDD KKKGEQVKAR MDFDMNQVRL RGFAKTLVHS EDQVRGSMST
LVQSVGLGGL KPNTMLISWP VHDREEDLTE YNTFIEKVHA ASINDMAIVV AKGIIDFPSA
VFRMSGMIDV YWIVHDGGLC LLMGYLLKQH KVWRGCKLRV IGIAQESDNN VKMQEDLQKY
VYQLRIDAKI MIVELADPEI SKNAFERTLL MEERTMMMRD LQKVSGGGMS LSLPPSNAPR
AVSPLVTSEK RENSKDSDDG TTGSEETSEK KSPTADNEQA NQDTKTKKER MKALDRSKVS
KMHTAVRLNE LLLQHSANSQ LILLNLPKPP VHKDEQALDD YVHYLEVMTD KLNRVIFVRG
TGKEVITESS
//
