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Database: UniProt
Entry: A0A261BHR6_9PELO
LinkDB: A0A261BHR6_9PELO
Original site: A0A261BHR6_9PELO 
ID   A0A261BHR6_9PELO        Unreviewed;      5209 AA.
AC   A0A261BHR6;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   07-NOV-2018, entry version 5.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OZG09743.1};
DE   Flags: Fragment;
GN   ORFNames=FL83_15641 {ECO:0000313|EMBL:OZG09743.1};
OS   Caenorhabditis latens.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=1503980 {ECO:0000313|EMBL:OZG09743.1, ECO:0000313|Proteomes:UP000216463};
RN   [1] {ECO:0000313|EMBL:OZG09743.1, ECO:0000313|Proteomes:UP000216463}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PX534 {ECO:0000313|EMBL:OZG09743.1,
RC   ECO:0000313|Proteomes:UP000216463};
RA   Fierst J.L.;
RT   "Caenorhabditis latens genome sequence.";
RL   Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:OZG09743.1}.
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DR   EMBL; NIPN01000135; OZG09743.1; -; Genomic_DNA.
DR   Proteomes; UP000216463; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0005219; F:ryanodine-sensitive calcium-release channel activity; IEA:InterPro.
DR   CDD; cd00051; EFh; 1.
DR   CDD; cd12877; SPRY1_RyR; 1.
DR   CDD; cd12878; SPRY2_RyR; 1.
DR   CDD; cd12879; SPRY3_RyR; 1.
DR   InterPro; IPR001870; B30.2/SPRY.
DR   InterPro; IPR013320; ConA-like_dom_sf.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR005821; Ion_trans_dom.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR013662; RIH_assoc-dom.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR013333; Ryan_recept.
DR   InterPro; IPR003032; Ryanodine_rcpt.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR009460; Ryanrecept_TM4-6.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   InterPro; IPR035761; SPRY1_RyR.
DR   InterPro; IPR035764; SPRY2_RyR.
DR   InterPro; IPR035762; SPRY3_RyR.
DR   InterPro; IPR003877; SPRY_dom.
DR   PANTHER; PTHR13715; PTHR13715; 3.
DR   Pfam; PF13499; EF-hand_7; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF00520; Ion_trans; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF08454; RIH_assoc; 1.
DR   Pfam; PF06459; RR_TM4-6; 1.
DR   Pfam; PF01365; RYDR_ITPR; 2.
DR   Pfam; PF02026; RyR; 4.
DR   Pfam; PF00622; SPRY; 3.
DR   PRINTS; PR00795; RYANODINER.
DR   SMART; SM00054; EFh; 2.
DR   SMART; SM00472; MIR; 4.
DR   SMART; SM00449; SPRY; 3.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   SUPFAM; SSF49899; SSF49899; 2.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50188; B302_SPRY; 3.
DR   PROSITE; PS00018; EF_HAND_1; 2.
DR   PROSITE; PS50222; EF_HAND_2; 2.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Calcium {ECO:0000256|PROSITE-ProRule:PRU00448};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000216463};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000216463};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4572   4595       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4760   4777       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4823   4845       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   4961   4983       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   5003   5028       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM   5088   5107       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      104    158       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      165    209       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      218    273       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      279    336       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      344    402       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      582    803       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1032   1214       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     1499   1718       B30.2/SPRY. {ECO:0000259|PROSITE:
FT                                PS50188}.
FT   DOMAIN     4317   4352       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   DOMAIN     4355   4387       EF-hand. {ECO:0000259|PROSITE:PS50222}.
FT   CA_BIND    4330   4341       {ECO:0000256|PROSITE-ProRule:PRU00448}.
FT   CA_BIND    4365   4376       {ECO:0000256|PROSITE-ProRule:PRU00448}.
FT   COILED     1026   1046       {ECO:0000256|SAM:Coils}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:OZG09743.1}.
SQ   SEQUENCE   5209 AA;  592182 MW;  6B97DB26EFE67C97 CRC64;
     MADKEEQGGG EQDDVSFLRT GDIVCLSCLT SHSKEGVQGS ERVCLCTEGF GNRMCTLENV
     ADKDIPPDIA MCMLYIDNAL SMRALQEMMS ADSDHKSASG AGGHKTLLYG HAVQLKHVQS
     EMFLACLSSC SSNDKLAFDV GVQETNEGEA CWWTIHPASK QRSEGEKVRV GDDVILVSVA
     TERYLHMAYN KGYMVIASFH QTLWNIQSVS SGSMRTRNMG FLFGNDVLRL FHGNDECLTI
     PENWSEHPQH NMVIYEGGAA VTQARSLWRV ELVRMKWHGA LVGWEQVFRI KHITSGRYLG
     VLDNAVQLYH KEKADFDLTA FVMCQNKDPK KQMLEEKEEE GMGTATIRYG ETNAFIQHVK
     TQLWLSYQTT EVTKKGLGKV EEKKAVALKD GHMDDCYTFF MALEEESKSA RVIRKCSSVL
     NKFLKGIDAL RELGNQSPDW TRVDLNEVLK LMEDLIEYFA QPNEEQEFED KQNHLRALRS
     RQDLFQEEGV LNMILDTIDK FSQMEALPDF AGLIGEETQI MWEQISTYLY LLVAAMIKGN
     HYNCAQFASA QRLDWLFGRL SNPQSAEGIL DVLYCVLTES PEALNMINEG HIRSVISLLE
     KVGRDPKVLD VLSSLCEGNG MAVRSSQNLI TQYLLPGKDL LLQTSMRDHV SSMMPNVMLG
     VVEGSALFRK WYFEAEVEHI ETMTKQAPYL RIGWANSVGF KPFPGSGDKW GCNGVGDDFY
     SYGFDGKSMF FGGKSRIVGH KLLEKGDVIG CSIDLTIPEI RFSVNGTYMS GTFKKFNIDG
     YFFPVMSLSA KVSCRFILGG NQGRLRYGPP TGFSAVVEAV NGELGISDCL SFGDLGKNIF
     CGPQTIFNNL EPFIPTPIDV STTQLTHHAI EKHHSYAENL HELWAMRKIE LGWSYGENRS
     ETSRKHPCLT KFELLPETEK KYNIMLALTT MKTIEALGYH LITDDPPCRL RAVRLGPNFQ
     QPNGYKPGPL DTHEITLPAE LQPLIEALAR NTHNVWAKEK IKRGWTFGLS EHVDATQKRS
     PHLVPYEQVD ERIKQANRES AAENIRALQL FGIFLEPPAH EHDEIAEKEL RARKDNTRTY
     RAEATYAVNG GKWYFEFEIL TAGFMKIGWM DIGSTPEIQL GADDRSYAFD GYLGRKWHQG
     AETYGKEWKI GDVVGCFLDL NDRTISFSLN GELLLDPSGS EMAFDNVVCG DGLVPAMTLG
     SGQRGRLNFG QQSNSLKFFT TCGLQEGYEP FCVNMYRTMP MWFAKQLPRF EDISTLKSGS
     ILEVSRFPAT GNSPPCLKIL QKVTISEGGP SEKAKMEYIR LSLPVKCNDT FVKNKDKEAI
     RRQLQDYKER SQSVVSQIRA PTIPKEFDDN KEKKGFLRSM LGSKDSHESD DDRRSRTTSK
     QPSMEGDEPP AVRRSLLELP HEERQIAEDH MRDMSDRHAE KPKKGGLLSR LRDSSNTRKK
     DSDRRKEDKA AALRQMKSNS RSFDAGSLDT STLPTGQKDV LEEESEEQDP IWVLQDQFHE
     EDTVSASSEM PLSGPGRQLT IKRGSIKKNK KGKKGEHALE KIEREKKGSI IPPEAQMDVL
     QVGDGPALIA LKDKVDEYYY GLRIFPGQDP SQVWVGWVTT QYHYYNLNFD GSQGVRKCRF
     SEADHHGTTV DSVQSQNCYM VNVSELLATT PDVANTKVSG TLIGCIIDTS IGELSFQVGT
     TDTGIKFKLE PGAMLFPAAF VTPTATEVVQ FELGRVKFTF PLSAAMFKSC EKSLVPFCPP
     RLTVEQIESI YWARWSVLCN DPVRIMSVYI PEKDQSLDIL EMIEMPDMLE FHRQTLNLYC
     KLASHGNHKV AHTLCQHIDE DQIMYAIKSH YLSGPMRQGF HDLLIGLHLM SHTAARNSMA
     KEYVIPLVPQ LQIKNVLDPD SESRYPQITG QSVSMLSQMA SEPVKKHISR EEEMKLLPPS
     VDFEALKKHV MESLQSATHH AVMNCRDLIG GDNTNHFEPL FKLFDQLLVI GLINDEELEC
     LLRLIHPQAF DESYENGTTQ KGLTQLELAE PVKLQLVSIL DHLCDIQLRY RIESLVAFTE
     GFVGELQSDQ CKRYMEIKQT DMPPAEAAKK TKEFRCPPKE QMFRLLMCKV KEERDPEIME
     EDVDVDQCPM AESLQQQLRD FCELLVAKIG NAKEGDSEEQ LSLIESEEGS WVDSFARIVV
     KVPPPLQEEG LEMQKKGTQN FREIIVTMLR EWAQADFIES KDLIRCMFKL LLRQYSGIRE
     IRDAMSQAYV FHERNAEDVT DFIVYLIQIR ELLTVQFEHT EEAILKRGLW KLMNNRIFFQ
     HPDLMRLLSV HENVMSIMMN ILTAQQGTVE HEGDEVKEKA PIKDASEMVV ACSRFLCYFC
     RTSRQNQKAM FEHLSFLLDN ATMLLARPSL RGSVPLDVAY SSFMDNNELA LALKEEELDK
     VAVYLSRCGL QPNSELITKG YPDIGWDPVE GERYIDFLRF CVWINGENVE ENANLVIRLL
     IRRPECLGVA LKGEGQGLFS AFKEAIALSE DIRLLENDSH PAMLTSGLLG ENPTYPSKEI
     EGEDYIDLGA ATLDFYSSLV DLLAKCAPDP MAIQAGKGDS LRARAILRSL ISLDDLGQIL
     ALRFTIPNLA APSVEAVRRA NAVQASHTQK AVMAHTFAMV ASLASEVSNT RRSQTFTSGA
     NLARRGLPCV EEVDTDDSKS SDYASVHTSF SSGNELFVPK SEKEKAELQL LNEKKYPIVQ
     RRRSSRYNPI DNTGPLPGLL PNHKGSVLLF LDRVYGIDQQ DMLFHFLEQS FLPDLRAATM
     MDSPRALESD TALALNRYLC NSVLPLLTNH SHFFSDAEHH SALLDATLHT VYRMNRLKSL
     TKNQRDAVSD FLVAITRELP PAMMIKLLKK VINDILTMND MNVLVPLRLI TLHYERCGKY
     YGSGNHYGVA SEQEKRLSML LFDAIFDTLG SRPYDPELFG KALPCMTAIG SAISPDYTLT
     SGLEDVRNKK REEEGAWIPR TVDVSRCEIP RDLEKMTELF AEHFHDSWAS RKLEKGWVHG
     DLYSRANATH PRLKPFSLLK DFEKSFYKER CSECLRALMA WNYKFEMIDR DANDRASAAR
     AISGTSISNF SPKPIDLSSM TLEKDMVNAA EKMAEHSHLI WAKKIMNDLN TKGGFMPIPL
     VPWDLLTDFE RRKDRFRASE ILKFLQYHGY HVDPKDEQSQ NDRMKSEGER TSVEKRFAYN
     LLEKLITYLE QASLKMKSVK PSQELTRRNS FKKEGQDVKF FEKVVLPLMH AYFNAHKSYF
     LEGSSIVQTG TASNKEKEMV ANLFCRLAAL LRIKNRAFGS VAKITVKCLQ GLTQALDLRT
     LVKVNSDIVR TSLLTFFNNC ADDLYAAVNE LKDGGQYSLI RGQALKSWNS FEFANQMIVP
     VLTTMFAHLA RNHFGTDLLL DDIQAACYKI LDSLYMVTGL SSSIAHRKSI SGESEKHRPG
     LGQCLAAFAS CFPVAFLEPE FNKSNKFSVL AKSQDQSVQV QEMLQNLSTH IPHLEKLLTD
     IETVANNNTM YSDVPNVYDV DLPLMCSYMA HWFSVGPEGK RDKDDQRASV VQTTSVSCDH
     INRIFNALLK MIRNHVGIEN APWLCRVNFF AVQIIQNVTS DPVREFVLPI AERLRRMSEK
     AYKEEEHMRT HPDDADEGTV AEDNARLVRD TYAFFPILMK YTDLHRAQWL KSPTWETDGV
     YENVAVIFRI WSQSQHFKRE ELNYVAQFEE DAAAMGGGDM KTGKAAIAER KKKRREGQDK
     MKEYFDRNGR PIIKKDKHAA SIVIACLKRL LPVGLNVFGG RELDIVQQSK EKFIQKETEE
     KIREFIKGLL EIPVKTDPTD KNAWQLSLYR KIGKSQMRGK DEMSQEAVIE KIFNMGQVSA
     ILHTITRTKD RRRRAHHRWK MTSRMEKEDI WKKVLTLQRK RMAISLITAS HLYKTELHRG
     INFFLPAFSR LWLEEEDVGQ DQLIADICSG VEEEEGPRIE IIMEEGVPIV ASSEETNQKE
     TNPDPLKQLI RCFQRAATSE ETAASAIHED SLYIRFADVM AKSIHIEEED GDDGDEGEID
     QAAKEEQSQA LRGEQAVLAS RGAAIMCLMY LSASGGEPNE MVAQTLQLGI HLLSGGNVEI
     QKMLIEYLQL KKDVRFFTSM AGLMNKCSVL NLEMFERQIK AEGLGMGAEL ASGDNQNLND
     ADFTCSLFRF LQLTCEGHNL EFQNYLRTQP GHTTSVNLIN CTVDYLLRLQ ESVMDFYWHY
     SSKEVIDEGG KEYFLRAIQG PCVGNQMTLA NSRLWDAING FFFLFAHMME KLYKNSTQLE
     LLREFLNLQK DMIVLMLSML EGNVLNGSIG KQMVDALVES QPSVEKILKF SDMFLKLKDL
     TTSQAFQDFD TNQDGWISPK EFQRAMESQK MYTVEDITYL MMCTDVNNDG KVDYMEFTER
     FHNPARDIGF NLAVLLVNLK EHITNDPRLE KIIEKAQTLL EYFDPFLGRI EIMGSSKRVE
     KIYFEIQESW LEQWGKQQIR DSKNSFLFNV LQDDGGDQGK LEAFINFCED TIFEMQHAAA
     ISSGDSDTKM ERAIKQRDYF LQQTTASDQI SETFKSGYNY GISAASALSP QNISTTMKNV
     TTSVRQMTWT QLLYSIIILL IRAGLAIGWG AYLLLMTIFR FAYFLTTSSE EEESSKHDNA
     KEQTKMNHDH ATFSPPIVQD FHHSHVGVDA FGVGMNADHL NVNSLPDFVP PPRPETPETV
     LPEEEKLLNQ DIPSPTSPAA ASKAPSIYES IGAPQMVQLQ SEADFQQGQY EPKIAESNST
     KTRGSILNML ARNFKTIEKI TLYLAFFINV ILLFHRVDIS HTENQEAASE GDDDEEAVES
     IFITGMQFPY VEYEITGWML AQILYWISVL HLSTSFALLV SFYQLKIPLI TFKREKEIAR
     KLMFDGCWIT EEDSEELGIV DTFMWYLDRI VISAKSFPMM YWDKFVRRKT RSKFKDQVDE
     ETLTSILGEE KMSTDSSYDY RYSCWLWVGV ILTNGQFLYR VGYLLCSACG VFVSPFFYAF
     HLVDVVLSFP MLKAILQSVT HNLQQLILTI MMTLVVVYLY TVIAFNFFRK FYVQEGEDGE
     EPDRKCHNML TCFIYHFYAG VRSGGGIGDE LESPYGDDLE YPRMFYDISF FFFVIIILLA
     IMQGLIIDAF GELRDQQESA TEKLESSCFI CDIGKETFDR MPRGFEIHTT KEHNFANYLF
     FLQHLVNKDE TEYTGQETYV REKYDNRDWD FFPVGECFVK QYEDQLLQS
//
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