ID   A0A261BI19_9PELO        Unreviewed;       682 AA.
AC   A0A261BI19;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   RecName: Full=Amino acid permease/ SLC12A domain-containing protein {ECO:0008006|Google:ProtNLM};
DE   Flags: Fragment;
GN   ORFNames=FL83_15732 {ECO:0000313|EMBL:OZG09927.1};
OS   Caenorhabditis latens.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=1503980 {ECO:0000313|EMBL:OZG09927.1, ECO:0000313|Proteomes:UP000216463};
RN   [1] {ECO:0000313|EMBL:OZG09927.1, ECO:0000313|Proteomes:UP000216463}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PX534 {ECO:0000313|EMBL:OZG09927.1,
RC   ECO:0000313|Proteomes:UP000216463};
RA   Fierst J.L.;
RT   "Caenorhabditis latens genome sequence.";
RL   Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OZG09927.1}.
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DR   EMBL; NIPN01000132; OZG09927.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A261BI19; -.
DR   STRING; 1503980.A0A261BI19; -.
DR   Proteomes; UP000216463; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015377; F:chloride:monoatomic cation symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 2.
DR   InterPro; IPR004841; AA-permease/SLC12A_dom.
DR   InterPro; IPR018491; SLC12_C.
DR   InterPro; IPR004842; SLC12A_fam.
DR   PANTHER; PTHR11827:SF72; GH08340P; 1.
DR   PANTHER; PTHR11827; SOLUTE CARRIER FAMILY 12, CATION COTRANSPORTERS; 1.
DR   Pfam; PF00324; AA_permease; 3.
DR   Pfam; PF03522; SLC12; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000216463};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        88..109
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        121..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        167..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        273..291
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        321..341
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        372..391
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          100..189
FT                   /note="Amino acid permease/ SLC12A"
FT                   /evidence="ECO:0000259|Pfam:PF00324"
FT   DOMAIN          240..314
FT                   /note="Amino acid permease/ SLC12A"
FT                   /evidence="ECO:0000259|Pfam:PF00324"
FT   DOMAIN          318..400
FT                   /note="Amino acid permease/ SLC12A"
FT                   /evidence="ECO:0000259|Pfam:PF00324"
FT   DOMAIN          438..525
FT                   /note="SLC12A transporter C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF03522"
FT   REGION          28..79
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:OZG09927.1"
SQ   SEQUENCE   682 AA;  73928 MW;  603B1E94F556615E CRC64;
     MSNDGSTIFG GGGGSSVTSY GGIVNEMFDS GGGPVDGPPI SANGKSPKKG AVPLIDEDSQ
     STPRGSTAGD GGAGSPSMEF ANSRPGGLST ISGVFAPVAL SMFSILLFLR MGFVVGQLGF
     LMTILQLAMA YAIVMLTVLS LCAISSNGAV EGGGVYYMIS RSLGPEFGGA IGVLFFVANV
     FSCALYISGF TEALMNNIGN GLCFNGHMEV AIPKVNTPAY RVPVNVSDPS QGMVEDFNQN
     LTANYTGWSF HTLGENMFPN YTMDYTTEKP TDFALMFAII FSGVTGLMAG ANMSGELARP
     SVSIPRGTVQ AVMMDTNFHR IFILIGIFST TLFSSMSNLI GSSRVLNRLS HDKLFGCLLR
     PAKIEIGDRN PVVSVVITWI CVVLVFLAPS VSSGSISQAL IYHQVRKYLL LLDVRKEHVK
     YWRPQILLLV SRPASACSLL DFVNDLKKSG LYVVGHVRKG DMDSSVPVDP LQQVFPYWLS
     LIDYLKLKAF VELTMSNNIR HGIQQLMRLS GLGAMKPNTV VIGFHELAPS QVTLQESQLL
     KDLRFSKIDR AAVVEYFTAG DYMPKELDGN LERLSPVDYV NVLKDVLHMT KNLCVARHFS
     KLDKEALSRG WNGQKRYIDV AFNDMVKRYS EEAAITLLNL PVPPDNAEDD GDRYLEMVRN
     LTDALPPTLL VHGVSSVIST AL
//