ID A0A261BQ17_9PELO Unreviewed; 398 AA.
AC A0A261BQ17;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 03-MAY-2023, entry version 23.
DE RecName: Full=Delta-like protein {ECO:0000256|RuleBase:RU280815};
DE Flags: Fragment;
GN ORFNames=FL83_12901 {ECO:0000313|EMBL:OZG12399.1}, FL83_23331
GN {ECO:0000313|EMBL:OZF86030.1};
OS Caenorhabditis latens.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=1503980 {ECO:0000313|EMBL:OZG12399.1, ECO:0000313|Proteomes:UP000216463};
RN [1] {ECO:0000313|EMBL:OZG12399.1, ECO:0000313|Proteomes:UP000216463}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PX534 {ECO:0000313|EMBL:OZG12399.1,
RC ECO:0000313|Proteomes:UP000216463};
RA Fierst J.L.;
RT "Caenorhabditis latens genome sequence.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Putative Notch ligand involved in the mediation of Notch
CC signaling. {ECO:0000256|RuleBase:RU280815}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU280815}; Single-
CC pass type I membrane protein {ECO:0000256|RuleBase:RU280815}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OZG12399.1}.
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DR EMBL; NIPN01000425; OZF86030.1; -; Genomic_DNA.
DR EMBL; NIPN01000093; OZG12399.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A261BQ17; -.
DR STRING; 1503980.A0A261BQ17; -.
DR Proteomes; UP000216463; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005112; F:Notch binding; IEA:InterPro.
DR GO; GO:0001708; P:cell fate specification; IEA:InterPro.
DR GO; GO:0007219; P:Notch signaling pathway; IEA:InterPro.
DR Gene3D; 2.10.25.140; -; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR001774; DSL.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR039178; Lag2.
DR PANTHER; PTHR22669; DELTA/SERRATE/LAG-2 DOMAIN PROTEIN; 1.
DR PANTHER; PTHR22669:SF8; PROTEIN LAG-2; 1.
DR Pfam; PF01414; DSL; 1.
DR Pfam; PF00008; EGF; 1.
DR SMART; SM00051; DSL; 1.
DR SMART; SM00181; EGF; 2.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR PROSITE; PS51051; DSL; 1.
DR PROSITE; PS00022; EGF_1; 2.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS50026; EGF_3; 2.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|RuleBase:RU280815};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076,
KW ECO:0000256|RuleBase:RU280815};
KW Membrane {ECO:0000256|RuleBase:RU280815, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000216463};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|RuleBase:RU280815};
KW Signal {ECO:0000256|RuleBase:RU280815, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|RuleBase:RU280815, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|RuleBase:RU280815,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..15
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 16..398
FT /note="Delta-like protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5011914672"
FT TRANSMEM 284..303
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 120..164
FT /note="DSL"
FT /evidence="ECO:0000259|PROSITE:PS51051"
FT DOMAIN 169..213
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 226..263
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 122..131
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00377"
FT DISULFID 135..147
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00377"
FT DISULFID 155..164
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00377"
FT DISULFID 203..212
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 253..262
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:OZG12399.1"
SQ SEQUENCE 398 AA; 44144 MW; 1DF9F4E7C11B9966 CRC64;
MLLLGLLIFL PLITCKVEVR QEFVTSERVS MRFEIITNDG SRPNPMNFSL FPRAPKTNTV
HLNTFDSAFN YSIQLLQPFT KQALGDRIYR QVHFSNINQP WFNDTFTTSS GIVLSISTRI
GCTPHYYGSQ CEVFCDGHLA KAARKRCDAM GRLRCDIGWM GPHCGQAVDP RKCSCHNSGI
CASSMIHSLE KIQNKTEQLI CECTNGYTGN NCEVPGFTQF QFTAPQPDAC SVKDACLNGA
KCFPNGPKVF CACAVGFIGE FCEISLTTTT PSVEITASTS DYSVTIYSVV GIFIGLCLLI
GCCKYKLTHK REHALARGLA PEPYPMPETK SMLVDQEACE AENQKNKKVF TIGDNVKQVD
EEVRYTSAPR ISNEYAVIQK PPPPTVCLPR IPVTCVYV
//
