ID A0A261C1W6_9PELO Unreviewed; 534 AA.
AC A0A261C1W6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=EGF-like domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=FL83_09604 {ECO:0000313|EMBL:OZG15975.1};
OS Caenorhabditis latens.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=1503980 {ECO:0000313|EMBL:OZG15975.1, ECO:0000313|Proteomes:UP000216463};
RN [1] {ECO:0000313|EMBL:OZG15975.1, ECO:0000313|Proteomes:UP000216463}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PX534 {ECO:0000313|EMBL:OZG15975.1,
RC ECO:0000313|Proteomes:UP000216463};
RA Fierst J.L.;
RT "Caenorhabditis latens genome sequence.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OZG15975.1}.
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DR EMBL; NIPN01000050; OZG15975.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A261C1W6; -.
DR STRING; 1503980.A0A261C1W6; -.
DR Proteomes; UP000216463; Unassembled WGS sequence.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 3.
DR CDD; cd00109; Kunitz-type; 1.
DR Gene3D; 2.10.25.10; Laminin; 3.
DR Gene3D; 4.10.410.10; Pancreatic trypsin inhibitor Kunitz domain; 2.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR002223; Kunitz_BPTI.
DR InterPro; IPR036880; Kunitz_BPTI_sf.
DR PANTHER; PTHR24049; CRUMBS FAMILY MEMBER; 1.
DR PANTHER; PTHR24049:SF22; DROSOPHILA CRUMBS HOMOLOG; 1.
DR Pfam; PF00008; EGF; 2.
DR Pfam; PF07645; EGF_CA; 1.
DR Pfam; PF00014; Kunitz_BPTI; 2.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00179; EGF_CA; 3.
DR SMART; SM00131; KU; 2.
DR SUPFAM; SSF57362; BPTI-like; 2.
DR SUPFAM; SSF57196; EGF/Laminin; 3.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS50279; BPTI_KUNITZ_2; 2.
DR PROSITE; PS00022; EGF_1; 2.
DR PROSITE; PS01186; EGF_2; 2.
DR PROSITE; PS50026; EGF_3; 3.
DR PROSITE; PS01187; EGF_CA; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Reference proteome {ECO:0000313|Proteomes:UP000216463}.
FT DOMAIN 8..48
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 70..126
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 165..227
FT /note="BPTI/Kunitz inhibitor"
FT /evidence="ECO:0000259|PROSITE:PS50279"
FT DOMAIN 305..344
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 348..392
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 423..496
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 429..443
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..496
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 315..332
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 334..343
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 382..391
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:OZG15975.1"
SQ SEQUENCE 534 AA; 61265 MW; 84CDDE4494F02B33 CRC64;
MRRTNMENID ECRGYKAVCD KNAWCVNEIG SYKCECMASY RGDGKHCTYV GLGRSSIDCK
DCSIHATYSC LDKFDHDYKD TCSNENWRPH FYFNHQTRMC EQFWYDGCRG RSRNIFSEYD
TCTAMCEETN VLTRADAMIP RGHHITSHNH VITQRRSRRL DDRRCSLDFR ISLIVFTQLV
LLIDCRQWQQ RYYFDHASLT CRQFWFDGCR SDSRNIFDDQ LTCQWLCESQ PMYKSRSCLE
DFDEGLKKEC NGGRWRQQYY FDKGSKLTCL HTCENPAKKD PKKPWHNNDK FKMKEIIGDI
YKPNVTDTCL AKNPCKHNGT CIFVWKKDTH YCKCQPGYHG NNCEKIVDFD PCAEKPCLNG
ATCQLKYNDD DVDEKPTYEC FCAAGFGGPK CDERPCETNP CLNNGTCRTT KGYKTGGGIG
GASGTGLKAP AGNGTTESGG GGSSGEKSGE KKSGKNKKNP ATRKREREER EKKEAEIQAA
EEEEKQRKDY EEELQRKKAE EMELEAKKAL ETANSGIHLM PLALILALVL LRDI
//
