ID A0A261C6N9_9PELO Unreviewed; 1222 AA.
AC A0A261C6N9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OZG18159.1};
DE Flags: Fragment;
GN ORFNames=FL83_07507 {ECO:0000313|EMBL:OZG18159.1};
OS Caenorhabditis latens.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=1503980 {ECO:0000313|EMBL:OZG18159.1, ECO:0000313|Proteomes:UP000216463};
RN [1] {ECO:0000313|EMBL:OZG18159.1, ECO:0000313|Proteomes:UP000216463}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PX534 {ECO:0000313|EMBL:OZG18159.1,
RC ECO:0000313|Proteomes:UP000216463};
RA Fierst J.L.;
RT "Caenorhabditis latens genome sequence.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479,
CC ECO:0000256|RuleBase:RU003762}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}.
CC -!- SIMILARITY: Belongs to the integrin alpha chain family.
CC {ECO:0000256|ARBA:ARBA00008054, ECO:0000256|RuleBase:RU003762}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OZG18159.1}.
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DR EMBL; NIPN01000030; OZG18159.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A261C6N9; -.
DR STRING; 1503980.A0A261C6N9; -.
DR Proteomes; UP000216463; Unassembled WGS sequence.
DR GO; GO:0008305; C:integrin complex; IEA:InterPro.
DR GO; GO:0048513; P:animal organ development; IEA:UniProt.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR Gene3D; 1.20.5.930; Bicelle-embedded integrin alpha(iib) transmembrane segment; 1.
DR Gene3D; 2.130.10.130; Integrin alpha, N-terminal; 1.
DR Gene3D; 2.60.40.1460; Integrin domains. Chain A, domain 2; 1.
DR Gene3D; 2.60.40.1510; ntegrin, alpha v. Chain A, domain 3; 1.
DR Gene3D; 2.60.40.1530; ntegrin, alpha v. Chain A, domain 4; 1.
DR InterPro; IPR013517; FG-GAP.
DR InterPro; IPR013519; Int_alpha_beta-p.
DR InterPro; IPR000413; Integrin_alpha.
DR InterPro; IPR018184; Integrin_alpha_C_CS.
DR InterPro; IPR013649; Integrin_alpha_Ig-like_1.
DR InterPro; IPR048285; Integrin_alpha_Ig-like_2.
DR InterPro; IPR048286; Integrin_alpha_Ig-like_3.
DR InterPro; IPR028994; Integrin_alpha_N.
DR InterPro; IPR032695; Integrin_dom_sf.
DR PANTHER; PTHR23220; INTEGRIN ALPHA; 1.
DR PANTHER; PTHR23220:SF133; INTEGRIN ALPHA-PS2; 1.
DR Pfam; PF01839; FG-GAP; 3.
DR Pfam; PF08441; Integrin_A_Ig_1; 1.
DR Pfam; PF20805; Integrin_A_Ig_2; 1.
DR Pfam; PF20806; Integrin_A_Ig_3; 1.
DR Pfam; PF00357; Integrin_alpha; 1.
DR PRINTS; PR01185; INTEGRINA.
DR SMART; SM00191; Int_alpha; 5.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 1.
DR SUPFAM; SSF69179; Integrin domains; 3.
DR PROSITE; PS51470; FG_GAP; 5.
DR PROSITE; PS00242; INTEGRIN_ALPHA; 1.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889,
KW ECO:0000256|RuleBase:RU003762};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Integrin {ECO:0000256|ARBA:ARBA00023037, ECO:0000256|RuleBase:RU003762};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU003762};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU003762};
KW Reference proteome {ECO:0000313|Proteomes:UP000216463};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU003762};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003762};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU003762}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|RuleBase:RU003762"
FT CHAIN 26..1222
FT /evidence="ECO:0000256|RuleBase:RU003762"
FT /id="PRO_5011828176"
FT TRANSMEM 1151..1173
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU003762"
FT REPEAT 27..94
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 234..290
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 291..345
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 362..421
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 425..488
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT DOMAIN 473..644
FT /note="Integrin alpha first immunoglubulin-like"
FT /evidence="ECO:0000259|Pfam:PF08441"
FT DOMAIN 646..794
FT /note="Integrin alpha second immunoglobulin-like"
FT /evidence="ECO:0000259|Pfam:PF20805"
FT DOMAIN 800..1139
FT /note="Integrin alpha third immunoglobulin-like"
FT /evidence="ECO:0000259|Pfam:PF20806"
FT REGION 896..956
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 978..1034
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 929..948
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 984..1000
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1019..1034
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:OZG18159.1"
SQ SEQUENCE 1222 AA; 135538 MW; DFE9B5EFF28BEE59 CRC64;
MREGSFPRPT RLLCLLLGLF SLVAAFNIDT KNVVLHHMAN NYFGYSLDFY NEQKGMPVLV
VGAPEAETTN PNLAGIRRPG AVYACSVNRP TCREVHVDKM KGNLKKLNGS HLVPIEDKAF
QFFGATVKSN DKHDKLLMCA PKYKYFYSKF EVIEPVGTCF YAENGFDKTE EFSSCKQEPA
RHGRHRLGYG QCGFSGAIPG KKNQDRVFLG APGVWYWQGA IFSQSTKNQT DRPNTEYGSK
EYDHDMMGYS TATGDFDGDG IDDIVAGVPR GNDLHGKLVL YTSKLKMMIN LTDEVSTQHG
QYCGGAVAVA DVNKDGKDDI IMGCPFYTDY GSVKDAKTQE RKPQYDVGKV IVFLQTAPGV
FGKQIAVVGD DQWGRFGHSL AAAGDLNLDG YNDVIVGAPY AGKNKQGAVY VIHGSKDGVR
EKPTQKIEAS QIGHGTARAF GFSVAGGVDV DGNGMPDIAV GAWKSGNAAV LLTKPVVTVT
GATEPESALI NVEEKNCDVD AKLGKQACRH INTCFKYEGK GDTPNDLEFD LSFSLDDHSP
EPRAYFLQKD VKGDRSIKVA SGSKTRDHPS SIEQRVRLEK GRQKCFRHRF FASSTMKDKL
SPIHWSVNYT YVESKSGKLR GDKLEPAIDT TVPLSFQNKI NIANNCGKDD LCVPDLKVTA
VADREKFLLG TQDNTMLINV TVQNGGEDSY ETKLYFDVPQ GFEYGGIETV GTDGSAPACS
PTSDEPDSDG KWTFACDLGN PLPANKVVSS VVRVTASSDK PPLAPISINA HVNSSNDEEA
HTIADNKVTF TIPVDFKNQL SLNGRSNPEQ VDFSMTNKTR PDVFDDNEIG PVVSHLYQIS
NRGPSEIDAA TLDIFWPSFS TEGGHLLYII TEPVVNPPNK GRCRVKQLQN VNPLNLRITN
EHVPTEPPVA KTPNEYSREE DDESYEDTTQ PQRTTSHRPS QHQTHQQGQV HVYERDEEKI
RQNTGNWQYV EDKKKKGDYE YIPDEQEYDG PEFEDDEDED FDRAGSKRVK RSPVPKKKKK
EGARSGEPRS EKARFSDLRE AVKLSKEAGG VVDYKGPLSR ASVDCNGLRC THIECDIYDL
KEDEFVLVEI FSRLYTNTLV DERNPGGDIS SLALARVTST KYNLPHKPTL ITAVSTNMNA
IASEEGRDLP WWLYLLAILI GLAILILLIL LLWRCGFFKR NRPPTEHAER RVDSQPAAHY
ADTQARYASQ DQYNQGRHGQ ML
//
