ID A0A261CF32_9PELO Unreviewed; 897 AA.
AC A0A261CF32;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 08-NOV-2023, entry version 21.
DE RecName: Full=DH domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=FL83_04468 {ECO:0000313|EMBL:OZG21137.1};
OS Caenorhabditis latens.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=1503980 {ECO:0000313|EMBL:OZG21137.1, ECO:0000313|Proteomes:UP000216463};
RN [1] {ECO:0000313|EMBL:OZG21137.1, ECO:0000313|Proteomes:UP000216463}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PX534 {ECO:0000313|EMBL:OZG21137.1,
RC ECO:0000313|Proteomes:UP000216463};
RA Fierst J.L.;
RT "Caenorhabditis latens genome sequence.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OZG21137.1}.
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DR EMBL; NIPN01000010; OZG21137.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A261CF32; -.
DR STRING; 1503980.A0A261CF32; -.
DR Proteomes; UP000216463; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:InterPro.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:2000431; P:regulation of cytokinesis, actomyosin contractile ring assembly; IEA:InterPro.
DR CDD; cd00160; RhoGEF; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 1.20.900.10; Dbl homology (DH) domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR035899; DBL_dom_sf.
DR InterPro; IPR000219; DH-domain.
DR InterPro; IPR026817; Ect2.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR16777; PROTEIN ECT2; 1.
DR PANTHER; PTHR16777:SF2; PROTEIN ECT2; 1.
DR Pfam; PF00621; RhoGEF; 1.
DR SMART; SM00292; BRCT; 2.
DR SMART; SM00325; RhoGEF; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF48065; DBL homology domain (DH-domain); 1.
DR PROSITE; PS50172; BRCT; 1.
DR PROSITE; PS50010; DH_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000216463}.
FT DOMAIN 190..276
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 345..543
FT /note="DH"
FT /evidence="ECO:0000259|PROSITE:PS50010"
FT REGION 287..341
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 749..786
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 846..897
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 287..326
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 327..341
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 749..780
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 846..885
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:OZG21137.1"
SQ SEQUENCE 897 AA; 102159 MW; DE15963D46318FA8 CRC64;
MDVSMLQSQE KRSRSMRKLA VWKGDIEEYK EIFDMINQQK EKRKIEVVPY ESLDELDSDW
REYTFFCGDF TSDLFHTLTN AQDSGASAHL IVGPAALSHK LQTAQDFMLL RPCRPLYCEL
MKNVTMKLST EVLNKRELVD MVHFMGGSVR KDSMTLVGVP TLRADWITES WKNRDDPYFD
VFKQDFIDKH SLGVFEGLSL YFHGFKKNEI DDMKINFINT KGTLVDDPSE ATHVVYNPIN
DIEPLPVSSN QVHVTQEWFW VSLHRGCCAL EDNFALPTGS LRRKLLDNSN TNSPLGKSSR
SHNSRSLSSM RDCSGEGPSS NRTPDYIYSN DDEENVCKSP RQPSKRLRVC MEMVETEKNY
VALLKLVVKF KQALETEISE NEFVTRTDVA MIFGKLDPIL ELHEKIYARL TAILNEAHTL
LSAVNGNKND DKNLDFAQVW IDAKEEMMRA YPQYLNSFDT IKCLFAKHDK ENSKFHTFCK
AKESSPEFHR LQLTDLMIKP VQRLPSVALL LNEMAKKSDS KLKCTAEQAA KVIDEVLKIA
NKILEKNDNL ISHFSKFTAI ESIPPILVAA NRMFLRELVV SPIASTSSRL SQFSKMKLFL
FHDVLVITKV RSEKNAMQRF ARHASLASLK AIKRKPYRYI DQIQLITMRS AFRIRAPGDF
SKFQEAQSHV HDVFVWCLIH RDEQGGDTET VFVSTDSEEV RDFLDDIHKK IMSNCGRYFF
QSDPFEVNDL NDAHVANLTN RYFRNLCGSK PQNGHDSQMN TTASERTSQN ELSHNETVMG
PPKPQSRMRR ALSNAQLTIT STLGFGRNPN RNSLARISEN SSFMTSPRVS CVPAALVNMT
SVGIPGGNCD SESTPKRGQR APLTSDTFTR TGALGRSTSM RRQPTGFSHS EKEPHRS
//
