ID   A0A261CFI2_9PELO        Unreviewed;      1336 AA.
AC   A0A261CFI2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:OZG21221.1};
DE   Flags: Fragment;
GN   ORFNames=FL83_04552 {ECO:0000313|EMBL:OZG21221.1};
OS   Caenorhabditis latens.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=1503980 {ECO:0000313|EMBL:OZG21221.1, ECO:0000313|Proteomes:UP000216463};
RN   [1] {ECO:0000313|EMBL:OZG21221.1, ECO:0000313|Proteomes:UP000216463}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PX534 {ECO:0000313|EMBL:OZG21221.1,
RC   ECO:0000313|Proteomes:UP000216463};
RA   Fierst J.L.;
RT   "Caenorhabditis latens genome sequence.";
RL   Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC       1.A.6) family. {ECO:0000256|ARBA:ARBA00007193,
CC       ECO:0000256|RuleBase:RU000679}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OZG21221.1}.
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DR   EMBL; NIPN01000010; OZG21221.1; -; Genomic_DNA.
DR   STRING; 1503980.A0A261CFI2; -.
DR   Proteomes; UP000216463; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.470.10; Acid-sensing ion channels like domains; 1.
DR   Gene3D; 1.10.287.770; YojJ-like; 1.
DR   InterPro; IPR001873; ENaC.
DR   InterPro; IPR005020; LIN-8.
DR   PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR   PANTHER; PTHR11690:SF261; DEGENERIN-LIKE PROTEIN DEL-10; 1.
DR   Pfam; PF00858; ASC; 2.
DR   Pfam; PF03353; Lin-8; 2.
DR   PRINTS; PR01078; AMINACHANNEL.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU000679};
KW   Ion transport {ECO:0000256|RuleBase:RU000679};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000216463};
KW   Sodium {ECO:0000256|ARBA:ARBA00023053};
KW   Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW   ECO:0000256|RuleBase:RU000679};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000679}.
FT   TRANSMEM        1102..1125
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1173..1203
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1233..1336
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1173..1202
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1314..1336
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:OZG21221.1"
FT   NON_TER         1336
FT                   /evidence="ECO:0000313|EMBL:OZG21221.1"
SQ   SEQUENCE   1336 AA;  154492 MW;  DD9A452DCC266E6F CRC64;
     MSMIYDFSQR PPNVIKQEHL QENLSRYSSP IPEPNPNYNL TLKQYNALEK RNNLARLPEN
     VSTRKVILGL MKDRPDLWKR RHQRIETDKW KELGLDVYQR TGVFVNVESL VHTFRKARES
     LSRKMKKCRT EGRSVLEMEL QLSQWELFSS FQFYYEFKLN NRHFDDEDDD DIEFLGLHNP
     SETIEQRDSS QNADNTAAYS ERGNSFDYLA GMNYDATEPI SKKPKLELTT DTDVEHIGYQ
     IKRAFSQYPE KETLIRKAMF AAILKFDDSN FQDLGELFTS LAAKYTTGDQ ARNESEPAYS
     RYRSRGALNR SRLNSRASLG SLTGRRITLV ETDSGLIEVE SDKQFLDAFK DANMDAVHHL
     NAANPVTRGL WCLIIIAFVI LVLVQCYSQI KLYISEPVAT NIEAEYPSKI PFPTVAICNN
     NQFRLTYLTG GRIMNRRSKS ISGSLLSTGH DIESVFDTVL RKSWDMDAVK FLRSAAHWKS
     RMILGCTWPN GTSCKLSDFK AVWTTTGLCW AINTDPHNPF EVTGSGEGHG LRLLLNVESY
     ERVDACTKHF RTKSLPGLKI LIYNQTDIPD SSLNGVNVPS GYSMDIPFKM QHRSKLPGVH
     CVEESDEQIE ASTDFNNPEN IRTCTLRKYM TEVENSCHCT LRRAYTSNST DLKMGACNVD
     QYFGCAQKAL KRVREEGTAS ACLPPCKSID YTAWQDMNRL PQNLMPALIE EQEEDDEDDV
     EQEELDENVA FSTVSGGETF SCEDSAYLDE KQVMRIKRDA HRAYEMQARH QEDIFLRSRR
     LITRLRNAIV SIERHKWGWH SDTFSGVVER LSNLTCFSNF SERHREVISI LESRPITSEE
     KKANQMFFLL DEKGFERNST RYMSIGDLKS RYGDKVDDVA EEIAIILRIM EKLWHVFMPD
     SYLRSINGDF SRMDRIIELM NQYELNKLQR RAWAEKMQSR QMKHFFEDDF YESYYQPLIK
     DLDTTLVKQI DEVQADWPKV EYYLQRGSAG KTGAIMFFGD GKKENRQKFE KLIIEMHDCA
     SGKLRKEAGK MLHSFKKSYR ELQAAYGKLF KEELPDYLEN FQFGNKFVGD NFAMVNIFLH
     RMNLEVWSQD RTYGFWSLAC DIGGALGLFL GASLLTIIEI VYLCIQYGLC GKRARNMKCI
     PMDALTRQMK KVATCSCCKK EVEKQREPIY KKKSQSYQRR YTAEEEEQAE RFRSRTSSED
     SKMRKNIWAQ MNDPSANSTL TPSEIKHFLD QVQRHSQPPK DQYYYHDPSY LGASSPTNRH
     DDNRESSTSG YHSSPRPPRT VPPRDESPIP DTEPISVSEF SDAHGVPLFR TPPPKRRAQK
     EQKTNDDDDD DKQSYV
//