ID A0A261CG61_9PELO Unreviewed; 666 AA.
AC A0A261CG61;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Translation initiation factor eIF2B subunit epsilon {ECO:0000256|ARBA:ARBA00044144};
DE AltName: Full=eIF2B GDP-GTP exchange factor subunit epsilon {ECO:0000256|ARBA:ARBA00044345};
DE Flags: Fragment;
GN ORFNames=FL83_04645 {ECO:0000313|EMBL:OZG20990.1};
OS Caenorhabditis latens.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=1503980 {ECO:0000313|EMBL:OZG20990.1, ECO:0000313|Proteomes:UP000216463};
RN [1] {ECO:0000313|EMBL:OZG20990.1, ECO:0000313|Proteomes:UP000216463}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PX534 {ECO:0000313|EMBL:OZG20990.1,
RC ECO:0000313|Proteomes:UP000216463};
RA Fierst J.L.;
RT "Caenorhabditis latens genome sequence.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}.
CC -!- SIMILARITY: Belongs to the eIF-2B gamma/epsilon subunits family.
CC {ECO:0000256|ARBA:ARBA00007878}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OZG20990.1}.
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DR EMBL; NIPN01000011; OZG20990.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A261CG61; -.
DR STRING; 1503980.A0A261CG61; -.
DR Proteomes; UP000216463; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0031369; F:translation initiation factor binding; IEA:InterPro.
DR CDD; cd11558; W2_eIF2B_epsilon; 1.
DR Gene3D; 1.25.40.180; -; 1.
DR Gene3D; 2.160.10.10; Hexapeptide repeat proteins; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR InterPro; IPR011004; Trimer_LpxA-like_sf.
DR InterPro; IPR003307; W2_domain.
DR InterPro; IPR044123; W2_eIF2B_epsilon.
DR PANTHER; PTHR45887; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON; 1.
DR PANTHER; PTHR45887:SF1; TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT EPSILON; 1.
DR Pfam; PF02020; W2; 1.
DR SMART; SM00515; eIF5C; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
DR SUPFAM; SSF51161; Trimeric LpxA-like enzymes; 1.
DR PROSITE; PS51363; W2; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW Reference proteome {ECO:0000313|Proteomes:UP000216463}.
FT DOMAIN 483..665
FT /note="W2"
FT /evidence="ECO:0000259|PROSITE:PS51363"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:OZG20990.1"
SQ SEQUENCE 666 AA; 75525 MW; 2C9AAA27D83E9EC2 CRC64;
MTPPSSAFKK ATKKEEPPLT AVVILDVFDQ RFAPIQESYP CIGTFPICNV PSVNLVLSWL
MRTEVKNVLL VVSGLNAQHV ETVLNEWKLA FVELTLVVCD GVTSVGDCMR EMVNRELITG
DFMLISNPTA VVSSDLSTQI AEFRKRRREN ADNVMTLLYS NRENPEGFVL GISSETQKLI
LYPHANSLNL VKAEKFHFYE GVEIRRDITT TGIALCSRLI ATQFSDNFDF TGIDDVVREI
LSKDDILGMS VHVDVLPSKD RAFCAYDYES LIILNTLMLE RWFYPLVPER SDPTRFFSAN
PRNLYLEEEG NEICIKANTW ILNDSCSTVA LGVKTKISYD TTIRNSCIGA HTEISSKTKI
FGSIIGKNCK IGENCQIEYA FIGDNVTIPS GTHIPKETII GNGVVFPKDL PTIQHSAIFR
KAIDEDKYEK LSSQPVGSVH VVKYRHGGPF WRRAVDGRTN FAVEVEDSGT EGSTSEEEDE
GLDDNVRQFY DEVFESMEKI LESENQVMRN LILEINSSKL ACNVSPEEVA KNVFAAFLEL
PHNQELRPTQ ALIERWNELF TNYYQSSSEG QKVDERKQKS QINLLLAVEE KFVREEGFRA
RTPNLVHFLY QQDILDDNAI IDWYKSIDIS MATDGIEAGV KTDLKERMRR IVDWLQEEDE
EESDDE
//
