ID   A0A261CNA6_9PELO        Unreviewed;       750 AA.
AC   A0A261CNA6;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=Metal transporter {ECO:0000256|RuleBase:RU369091};
DE   Flags: Fragment;
GN   ORFNames=FL83_02097 {ECO:0000313|EMBL:OZG23535.1};
OS   Caenorhabditis latens.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=1503980 {ECO:0000313|EMBL:OZG23535.1, ECO:0000313|Proteomes:UP000216463};
RN   [1] {ECO:0000313|EMBL:OZG23535.1, ECO:0000313|Proteomes:UP000216463}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PX534 {ECO:0000313|EMBL:OZG23535.1,
RC   ECO:0000313|Proteomes:UP000216463};
RA   Fierst J.L.;
RT   "Caenorhabditis latens genome sequence.";
RL   Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Metal transporter. {ECO:0000256|RuleBase:RU369091}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU369091};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU369091}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the ACDP family. {ECO:0000256|ARBA:ARBA00010484,
CC       ECO:0000256|RuleBase:RU369091}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OZG23535.1}.
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DR   EMBL; NIPN01000002; OZG23535.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A261CNA6; -.
DR   STRING; 1503980.A0A261CNA6; -.
DR   Proteomes; UP000216463; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0008340; P:determination of adult lifespan; IEA:UniProt.
DR   GO; GO:0010960; P:magnesium ion homeostasis; IEA:InterPro.
DR   GO; GO:1905941; P:positive regulation of gonad development; IEA:UniProt.
DR   CDD; cd04590; CBS_pair_CorC_HlyC_assoc; 1.
DR   Gene3D; 3.10.580.10; CBS-domain; 1.
DR   Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR   InterPro; IPR045095; ACDP.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   InterPro; IPR002550; CNNM.
DR   InterPro; IPR044751; Ion_transp-like_CBS.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   PANTHER; PTHR12064; METAL TRANSPORTER CNNM; 1.
DR   PANTHER; PTHR12064:SF23; METAL TRANSPORTER CNNM-2; 1.
DR   Pfam; PF01595; CNNM; 1.
DR   SUPFAM; SSF54631; CBS-domain pair; 1.
DR   PROSITE; PS51846; CNNM; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW   ProRule:PRU01193}; Reference proteome {ECO:0000313|Proteomes:UP000216463};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW   ProRule:PRU01193};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989, ECO:0000256|PROSITE-
KW   ProRule:PRU01193}.
FT   TRANSMEM        137..164
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU369091"
FT   TRANSMEM        197..216
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU369091"
FT   TRANSMEM        222..241
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU369091"
FT   TRANSMEM        248..272
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU369091"
FT   DOMAIN          133..312
FT                   /note="CNNM transmembrane"
FT                   /evidence="ECO:0000259|PROSITE:PS51846"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:OZG23535.1"
SQ   SEQUENCE   750 AA;  84130 MW;  C1C7C048F9A2721A CRC64;
     MHTEFGYRWK IGKNPIVSGV RIESDVNAPG FLGYSDAGEL LVEADTPVDI VIFGHGLEDV
     EMVAFTDSVC VTSEFNISES SFHIHKDMKI VFKYSFIAWP RPWRICLKSE SHGLNQIDDD
     RTWIQAVEKI HETYMPVWAQ SAILCLLFSI SALCSGLTLG LMALTPQELK ILMKSGTPSE
     QKYASAIYPM RIHGNRLLCT VIIMNVIVNT GITLLFDDMA EGLIAFVAST VGIVIFGEIL
     PQSICVKYGL AVGANTVFIT RFFMFILFPI TWPLGKILDK YAGVDIDVVN RSRMVEMLKM
     NMENNEACDI DLSTLKIAIG AMELTKKSVR DVMTDIDDVF MLSEDQVLNA ETMTRVSDSG
     YTRIPVYEGN NRNKVKNLLY VSDLALIGKD NNITVKAVAR FNKRRLRIVD ENMPLTALMD
     EFKMGDYHLA MVAKALDVKK HHNGKFVDDK MDNFILKSMK LVEATVLPAV DASEDHPVTL
     VGLITLEDIT EELLQAEITD ETDCYITDDA QKKRRTNTSK KSVAEMYCSE KKSDRLSLHM
     LEMTEKWLLE KTPLFSEMNP KAFENLIQQN IREVLIVPPK NSTSPGTLNL FEAGVMSKRF
     VLILEGKATI KFNEKDLVFD CGPWTCFGEA ILEKMEQCVR DGREPSTGFF FLPDYTLTVS
     GPCRFLQIST SSLLHSLRIT QFVKEIRTPK ISITNDDVTG TNSRKVSIMD NSPTGSRKRS
     STSVMSTLAL PTARLAAKIA SVEELKPLME
//