ID   A0A261FHZ3_9BIFI        Unreviewed;       767 AA.
AC   A0A261FHZ3;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Beta-galactosidase {ECO:0000313|EMBL:OZG58759.1};
GN   ORFNames=BTIS_0480 {ECO:0000313|EMBL:OZG58759.1};
OS   Bifidobacterium tissieri.
OC   Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC   Bifidobacteriaceae; Bifidobacterium.
OX   NCBI_TaxID=1630162 {ECO:0000313|EMBL:OZG58759.1, ECO:0000313|Proteomes:UP000216444};
RN   [1] {ECO:0000313|EMBL:OZG58759.1, ECO:0000313|Proteomes:UP000216444}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 100201 {ECO:0000313|EMBL:OZG58759.1,
RC   ECO:0000313|Proteomes:UP000216444};
RX   PubMed=28764658; DOI=10.1186/s12864-017-3955-4;
RA   Lugli G.A., Milani C., Turroni F., Duranti S., Mancabelli L.,
RA   Mangifesta M., Ferrario C., Modesto M., Mattarelli P., Jiri K.,
RA   van Sinderen D., Ventura M.;
RT   "Comparative genomic and phylogenomic analyses of the Bifidobacteriaceae
RT   family.";
RL   BMC Genomics 18:568-568(2017).
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC       {ECO:0000256|ARBA:ARBA00007401}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OZG58759.1}.
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DR   EMBL; MWWV01000003; OZG58759.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A261FHZ3; -.
DR   Proteomes; UP000216444; Unassembled WGS sequence.
DR   GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR   InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR006101; Glyco_hydro_2.
DR   InterPro; IPR006103; Glyco_hydro_2_cat.
DR   InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR   InterPro; IPR006104; Glyco_hydro_2_N.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR013783; Ig-like_fold.
DR   PANTHER; PTHR42732; BETA-GALACTOSIDASE; 1.
DR   PANTHER; PTHR42732:SF1; BETA-MANNOSIDASE; 1.
DR   Pfam; PF00703; Glyco_hydro_2; 1.
DR   Pfam; PF02836; Glyco_hydro_2_C; 1.
DR   Pfam; PF02837; Glyco_hydro_2_N; 1.
DR   PRINTS; PR00132; GLHYDRLASE2.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR   SUPFAM; SSF49785; Galactose-binding domain-like; 1.
PE   3: Inferred from homology;
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000216444}.
FT   DOMAIN          30..150
FT                   /note="Glycosyl hydrolases family 2 sugar binding"
FT                   /evidence="ECO:0000259|Pfam:PF02837"
FT   DOMAIN          168..265
FT                   /note="Glycoside hydrolase family 2 immunoglobulin-like
FT                   beta-sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF00703"
FT   DOMAIN          273..563
FT                   /note="Glycoside hydrolase family 2 catalytic"
FT                   /evidence="ECO:0000259|Pfam:PF02836"
SQ   SEQUENCE   767 AA;  85908 MW;  35DF3E46CD7F1181 CRC64;
     MRFSETLHDG WLFTKEAVDG VPAYAPGPEW EAVEVPHTWN AFDGQDGGSD YYRGACWYVR
     QLTLKPHAPE TRVYLEFQGA ANVAEVYVNG CKITEHVGGY STFRADITTA LMPGENVLAV
     KVSNEERTDV YPQMADFTFY GGLYRPVEVL YVSPTHFELD YHGGEGVTVS STIDDGTAVL
     DARAWVTEPA EGDVVNFQIF DDDGNEVASA AVPADLGDGN VRTEIVIPDA HLWQGVEDPY
     LYDVVATIIR HNEVLDEVSF LHGVREFRFD PQEGFFLNGK LTPLRGVSRH QDRLGKGNAL
     SLEDHVEDAY LIKELGANTI RLAHYQQSRD FYDLCDQLGF VIWAEIPFIS RMSDDPAAHQ
     DCLSQMTELV IQNFNHASIL MWGISNEILI GGDSPKLVEN LKEINDLAHS LDPTRVTTMA
     QVSSTPKDSE HNQITDILSY NHYFGWYGGH FEDNEAWLDD FHAMHPDRSF GLSEYGCEGI
     ISYHTDDPQC GDYSEEYQAL YHEHMARIID ERPWLWGTHV WNMFDFGCDA RKEGGVEGRN
     NKGLVTIDRK IKKDSFFIYQ AYWSAEPMVH ICSKRYARRA ADTIDVKVYS NQDEVALAVD
     GKPFATMAAS AQSDPHIFIF KDVPLADGYT HVTVRAGIAE DSATWQKVAE PYEPYKFVDP
     EGGNIVMNWF DDVSADDGLP VDAPYDEAYY SVHDTVSAIL DNPEASATVT NAASSLANMR
     IKASMLGVLG NKSLVEMFDQ LRNMSGGASD IPQKLAYLNK QLQQIKK
//