ID A0A261FLU3_9BIFI Unreviewed; 1276 AA.
AC A0A261FLU3;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Lipid II flippase MurJ {ECO:0000313|EMBL:OZG60152.1};
GN ORFNames=BMYO_0973 {ECO:0000313|EMBL:OZG60152.1};
OS Bifidobacterium myosotis.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=1630166 {ECO:0000313|EMBL:OZG60152.1, ECO:0000313|Proteomes:UP000216871};
RN [1] {ECO:0000313|EMBL:OZG60152.1, ECO:0000313|Proteomes:UP000216871}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 100196 {ECO:0000313|EMBL:OZG60152.1,
RC ECO:0000313|Proteomes:UP000216871};
RX PubMed=28764658; DOI=10.1186/s12864-017-3955-4;
RA Lugli G.A., Milani C., Turroni F., Duranti S., Mancabelli L.,
RA Mangifesta M., Ferrario C., Modesto M., Mattarelli P., Jiri K.,
RA van Sinderen D., Ventura M.;
RT "Comparative genomic and phylogenomic analyses of the Bifidobacteriaceae
RT family.";
RL BMC Genomics 18:568-568(2017).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OZG60152.1}.
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DR EMBL; MWWW01000009; OZG60152.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A261FLU3; -.
DR OrthoDB; 9786339at2; -.
DR Proteomes; UP000216871; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.
DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR CDD; cd13123; MATE_MurJ_like; 1.
DR InterPro; IPR004268; MurJ.
DR PANTHER; PTHR47019; LIPID II FLIPPASE MURJ; 1.
DR PANTHER; PTHR47019:SF1; LIPID II FLIPPASE MURJ; 1.
DR Pfam; PF03023; MurJ; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Cell shape {ECO:0000256|ARBA:ARBA00022960};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Peptidoglycan synthesis {ECO:0000256|ARBA:ARBA00022984};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 28..47
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 53..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 84..109
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 200..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 291..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 332..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 403..425
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 431..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 466..488
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 508..534
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1053..1074
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 556..593
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 905..924
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1078..1173
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 560..587
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1104..1146
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1147..1161
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1276 AA; 135145 MW; 8C1E028BB28E61DA CRC64;
MSSTVGRNSL IMATGTAASR VTGQLRTILL AAAIGTTGLA ANAYQAGSMI PQSVFTLVSG
GIFNAVLVPQ IVRTMKEKDA QERLNRLITL AIGLLLVMTL IMAAAAPLLT LLYVGGGDHQ
MIALTTAFTL WCMPQVFFYG LYTVLGQILA ARDHFVTYAW SSTGANVISC AGFAAFIMLF
GKANEQPLDF WTADKIALTA GTWTLGVAFQ ALILFLPLAR IGFKYRPSFG LTGFGLKAMG
PVALGSLGVV ITSEISGIVL TRAATLAPQY AHDLTGASLF SVAGNATYQN AYTLFVLPYS
LIAVSVSTAM FPKISRSVAA RDLDEARRDL GGALNNVGLL LMFFAAAMIV FPEPIIRALL
PSVSMDETML IAYALTALSV GIPPCSAFLL IQRTFYAFED GLHPFLSALL QYGLVSAFII
GGVMALPPEH WVTWIACSVT IGAFLALPPT LIMLRRRFDG HLGGRGIIIT YAKAVAAAVV
AGLVTWLLKG PVTDLFGVSI RHTGGHMGWF AALGICVVLT IVLAVVYVGM LWILRTPELT
GAVQAVTARL GRGKRAASSS GTIPKASPAD RISTSIPNIS NNHTEPDEPM KPQLGDTILN
RYTLVSSLRE EPGIAAWKAN DRVLAKDCQL FIVSNSQVLT TVDDIAGRIV ATKPAHHVPV
LKYRMQAGVL LAVMPLDRGL SVSEYLAGAG NVLSHDAMRS IIGETLQAIR PMLAGSPVNE
AITTDTVRLT ASGVEIADAP FTPLLADTLG LGVAQQQSRQ PEGPEQVAIR QLAALLYALL
THSPSQAEPH FDLSQLPMDT PGEFRVILKR GLNLIEADDP TLPMASLAEL EALLGDWKPL
SDMGSNSSTD IALPNVDGEC SIATAPLQPV AESDVNPIPA GLVSSQQLPT LSINTSAPNI
AMPAVPLPDA TGKNGAANGT QKDERRLFDF NNLSNAWQDE NLSGEDTGDW YSTFNPAPTS
AAVGNSRLTV PIPTGNLAEP APGETTSRIP IFDAAGREVA PGEESLRALE EEQARIAEIA
AIPPSFEPKN PPKKTVDAEL PNEHLFGNFT TKVVAIVVAV LVVAAATVWA VIAFRDSSSN
PADVSTGKSA AAGQWPEFDE SQVPFGSGTG SSASGDNESD SSSQSSSSDS SQTTNGSSSS
DSQSKKSEKA TTADKDSKAV PTPKHVNNTP YTISSANFLT NPGGQSGYAY YLHLDQPHDV
YRMTVTIRTS GGKGYIRANT TGDPTQGEQV AEFTFAEGGT TEIKFTKTVN AQDLILWVPT
DSMPQNQLYI QKVEVF
//
