ID   A0A261GES0_9GAMM        Unreviewed;       492 AA.
AC   A0A261GES0;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 13.
DE   SubName: Full=Mannitol dehydrogenase {ECO:0000313|EMBL:OZG69989.1};
GN   ORFNames=BTA51_28375 {ECO:0000313|EMBL:OZG69989.1};
OS   Hahella sp. CCB-MM4.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC   Hahellaceae; Hahella.
OX   NCBI_TaxID=1926491 {ECO:0000313|EMBL:OZG69989.1, ECO:0000313|Proteomes:UP000215632};
RN   [1] {ECO:0000313|EMBL:OZG69989.1, ECO:0000313|Proteomes:UP000215632}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CCB-MM4 {ECO:0000313|EMBL:OZG69989.1,
RC   ECO:0000313|Proteomes:UP000215632};
RA   Sam K.-K., Lau N.-S., Dinesh B., Go F., Amirul A.-A.A.;
RT   "Genome sequence of Hahella sp. CCB-MM4 and discovery of its potential
RT   applications.";
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OZG69989.1}.
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DR   EMBL; MRYI01000031; OZG69989.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A261GES0; -.
DR   OrthoDB; 271711at2; -.
DR   Proteomes; UP000215632; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0019594; P:mannitol metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR000669; Mannitol_DH.
DR   InterPro; IPR013118; Mannitol_DH_C.
DR   InterPro; IPR023027; Mannitol_DH_CS.
DR   InterPro; IPR013131; Mannitol_DH_N.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43362:SF1; MANNITOL DEHYDROGENASE 2-RELATED; 1.
DR   PANTHER; PTHR43362; MANNITOL DEHYDROGENASE DSF1-RELATED; 1.
DR   Pfam; PF01232; Mannitol_dh; 1.
DR   Pfam; PF08125; Mannitol_dh_C; 1.
DR   PRINTS; PR00084; MTLDHDRGNASE.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00974; MANNITOL_DHGENASE; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215632}.
FT   DOMAIN          28..193
FT                   /note="Mannitol dehydrogenase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01232"
FT   DOMAIN          221..465
FT                   /note="Mannitol dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08125"
SQ   SEQUENCE   492 AA;  55377 MW;  3AE5AC5838311923 CRC64;
     MTKLSAECLS GLDDSIIRPV YDRKAIRQGI VHIGVGGFHR AHQAIYTEQL LNRGKSLEWG
     ICGVGLRPED QGMRDALAAQ DYLYTLYELG DGDDTQTQVV GAIGDFILAQ DNPQKLIEKL
     SSPETRIVSL TITEGGYCTD DSTGEFNAHL PQIQHDLQHP ESPKTVFGYL SAALKLRRDR
     GVTPFTVMSC DNLPHNGEVA RKALLTFTGL QDQELARWID ENVSFPNAMV DRITPMTSDE
     HREQLRAATG IEDRWPVVAE PFIQWVLEDR FCNGRPEWEE VGVQFTDDVT PYEDMKIRLL
     NGSHLAMTYL GFLLGYRFAH ETMEDETLRR YVRSYMDLDV TSTLSPVPGI DLEEYKNTLI
     ERFSNREICD QLSRICSDGS SKFPKFVLPT LLDMMAQGKP LARVALIIAA WAHYLRGVDE
     KGERYSIPDP RAGWLQEAIA ETSNVVESFL GLEDVFGKTI PNSAEFVSAF QLQLERLQKF
     GVKATLEMTL GD
//