ID A0A261TU51_9BORD Unreviewed; 392 AA.
AC A0A261TU51;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN ORFNames=CAL25_08635 {ECO:0000313|EMBL:OZI52801.1};
OS Bordetella genomosp. 5.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Bordetella.
OX NCBI_TaxID=1395608 {ECO:0000313|EMBL:OZI52801.1, ECO:0000313|Proteomes:UP000216913};
RN [1] {ECO:0000313|EMBL:OZI52801.1, ECO:0000313|Proteomes:UP000216913}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AU10456 {ECO:0000313|EMBL:OZI52801.1,
RC ECO:0000313|Proteomes:UP000216913};
RA Spilker T., LiPuma J.;
RT "Complete and WGS of Bordetella genogroups.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OZI52801.1}.
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DR EMBL; NEVP01000005; OZI52801.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A261TU51; -.
DR OrthoDB; 9790967at2; -.
DR Proteomes; UP000216913; Unassembled WGS sequence.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:InterPro.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000216913}.
FT DOMAIN 18..371
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 392 AA; 43096 MW; D3221611C4DF7A21 CRC64;
MTSPVLFEER IADNGSRIGV ATLNAPQTLN GLSLEMVDLL DERLQRWAVD PAVALVILQG
AGDRAFCAGG DLQGLYRSMK EHQGEGPWAN AYARRFFEHE YRLDYRIHAF PKPILCWGSG
IVMGGGMGLM MGASHRVVSE TTRMAMPEIT IGLFPDVGGS WLLNRMPGRT GLFLALTGAN
LNGSDAFYAG MADFRLDTAR WDDFNEALLH EPWAAQPGGP GTGNIAPRSI NDGLLRQVLL
AHEPSAPLEP GPLRHNAFLV NSVAGSNRLE EVYEEIAELK DHADPWLARA AQTMLAGSPG
SARLAFALQN RLRLRSLEDV FRAEYVAALV ATSYGDFQEG IRALLIDKDK RPRWHPATLE
DATDAWVQQF FVEPWPEGTE HPLEDLGRAE LG
//
