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Database: UniProt
Entry: A0A261UJP6_9BORD
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Original site: A0A261UJP6_9BORD 
ID   A0A261UJP6_9BORD        Unreviewed;       375 AA.
AC   A0A261UJP6;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   08-MAY-2019, entry version 7.
DE   RecName: Full=Phospho-2-dehydro-3-deoxyheptonate aldolase {ECO:0000256|PIRNR:PIRNR001361};
DE            EC=2.5.1.54 {ECO:0000256|PIRNR:PIRNR001361};
GN   ORFNames=CAL28_20180 {ECO:0000313|EMBL:OZI61602.1};
OS   Bordetella genomosp. 11.
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Bordetella.
OX   NCBI_TaxID=1416808 {ECO:0000313|EMBL:OZI61602.1, ECO:0000313|Proteomes:UP000215767};
RN   [1] {ECO:0000313|EMBL:OZI61602.1, ECO:0000313|Proteomes:UP000215767}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AU8856 {ECO:0000313|EMBL:OZI61602.1,
RC   ECO:0000313|Proteomes:UP000215767};
RA   Spilker T., LiPuma J.;
RT   "Complete and WGS of Bordetella genogroups.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Stereospecific condensation of phosphoenolpyruvate (PEP)
CC       and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-
CC       arabino-heptulosonate-7-phosphate (DAHP).
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=D-erythrose 4-phosphate + H2O + phosphoenolpyruvate = 7-
CC         phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate;
CC         Xref=Rhea:RHEA:14717, ChEBI:CHEBI:15377, ChEBI:CHEBI:16897,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58394, ChEBI:CHEBI:58702;
CC         EC=2.5.1.54; Evidence={ECO:0000256|PIRNR:PIRNR001361};
CC   -!- PATHWAY: Metabolic intermediate biosynthesis; chorismate
CC       biosynthesis; chorismate from D-erythrose 4-phosphate and
CC       phosphoenolpyruvate: step 1/7. {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- SIMILARITY: Belongs to the class-I DAHP synthase family.
CC       {ECO:0000256|PIRNR:PIRNR001361}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:OZI61602.1}.
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DR   EMBL; NEVS01000004; OZI61602.1; -; Genomic_DNA.
DR   UniPathway; UPA00053; UER00084.
DR   Proteomes; UP000215767; Unassembled WGS sequence.
DR   GO; GO:0003849; F:3-deoxy-7-phosphoheptulonate synthase activity; IEA:UniProtKB-EC.
DR   GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0009423; P:chorismate biosynthetic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006219; DHAP_synth_1.
DR   PANTHER; PTHR21225; PTHR21225; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   PIRSF; PIRSF001361; DAHP_synthase; 1.
DR   TIGRFAMs; TIGR00034; aroFGH; 1.
PE   3: Inferred from homology;
KW   Amino-acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Aromatic amino acid biosynthesis {ECO:0000256|PIRNR:PIRNR001361};
KW   Complete proteome {ECO:0000313|Proteomes:UP000215767};
KW   Transferase {ECO:0000256|PIRNR:PIRNR001361,
KW   ECO:0000256|SAAS:SAAS00080156}.
FT   DOMAIN       64    358       DAHP_synth_1. {ECO:0000259|Pfam:PF00793}.
SQ   SEQUENCE   375 AA;  40673 MW;  AB1D7D7CAD376FE3 CRC64;
     MNRLDDPLHD REVGNADSTL DTTRIDDVRI GAVRPLISPA LLLDELPVSP GIQDLVEGTR
     ASIADVLHGR DDRLVVVVGP CSIHDHDQAM DYARLLKTAA DELKEDLLVV MRVYFEKPRT
     TVGWKGYIND PRLDGSYRIN EGLRRARELL LDIAGLGLPT GTEFLDLLSP QFIADLIAWG
     AIGARTTESQ SHRQLSSGLS CPLGFKNGTD GGVQIAADAI VAARASHAFM GMTKMGMAAI
     FETRGNDDTH VILRGGKQGP NYDAASIAAC CDILKRAGLR EQVMVDCSHA NSNKSHSRQV
     DVARDVGEQI AGGDRRIVGV MIESHLEEGR QDLKPGVPLR RGVSITDACL GWAQTEPVLR
     QLAQAVRQRR AGAAR
//
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