ID   A0A261V7R2_9BORD        Unreviewed;       366 AA.
AC   A0A261V7R2;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Cobalamin biosynthesis protein CobW {ECO:0000313|EMBL:OZI69642.1};
GN   ORFNames=CAL24_22770 {ECO:0000313|EMBL:OZI69642.1};
OS   Bordetella genomosp. 2.
OC   Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC   Alcaligenaceae; Bordetella.
OX   NCBI_TaxID=1983456 {ECO:0000313|EMBL:OZI69642.1, ECO:0000313|Proteomes:UP000215633};
RN   [1] {ECO:0000313|EMBL:OZI69642.1, ECO:0000313|Proteomes:UP000215633}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AU8256 {ECO:0000313|EMBL:OZI69642.1,
RC   ECO:0000313|Proteomes:UP000215633};
RA   Spilker T., LiPuma J.;
RT   "Complete and WGS of Bordetella genogroups.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC   -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC       subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OZI69642.1}.
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DR   EMBL; NEVT01000009; OZI69642.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A261V7R2; -.
DR   Proteomes; UP000215633; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd03112; CobW-like; 1.
DR   Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR036627; CobW-likC_sf.
DR   InterPro; IPR011629; CobW-like_C.
DR   InterPro; IPR003495; CobW/HypB/UreG_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR13748:SF62; COBW DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR13748; COBW-RELATED; 1.
DR   Pfam; PF02492; cobW; 1.
DR   Pfam; PF07683; CobW_C; 1.
DR   SMART; SM00833; CobW_C; 1.
DR   SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801}.
FT   DOMAIN          270..364
FT                   /note="CobW C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00833"
FT   REGION          228..248
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   366 AA;  41077 MW;  A7DB45D6A949ADAA CRC64;
     MNTQRSLDKM VPVTILTGFL GAGKTTLLKR ILTEYHGRRV AVIENEFGPE SIDNDLLVQD
     SEEEIIELSN GCVCCTVRGD LMRTLSDLRA KREAGQLSFE RVILETTGMA NPGPVCQTFF
     MDDDIAEYYR LDAVVTVVDA KHGMATLDAQ TEAQKQVGFA DRILVSKKDL VNEADYEALR
     ARLVRINPRA PISPVNFGDA DLKSIIDISG FNLNSILDID PDFLADEHPD AAHSHAHGHD
     HDHDHDHEGE CGDHCHHDHH HHHHHHDDEI GAFVFRSNKP FDPARLEEFL GGVVQVYGPD
     LMRYKGILYM KGINRRMLFQ GVHMMMGAEP GKPWTAAEKP FTKMVFIGRK LPQEIFTRGL
     EQCLAG
//