ID A0A263BY61_9BACI Unreviewed; 860 AA.
AC A0A263BY61;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 13-SEP-2023, entry version 17.
DE RecName: Full=DNA mismatch repair protein MutS {ECO:0000256|HAMAP-Rule:MF_00096};
GN Name=mutS {ECO:0000256|HAMAP-Rule:MF_00096,
GN ECO:0000313|EMBL:OZM58654.1};
GN ORFNames=CIB95_03545 {ECO:0000313|EMBL:OZM58654.1};
OS Lottiidibacillus patelloidae.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Lottiidibacillus.
OX NCBI_TaxID=2670334 {ECO:0000313|EMBL:OZM58654.1, ECO:0000313|Proteomes:UP000217083};
RN [1] {ECO:0000313|Proteomes:UP000217083}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SA5d-4 {ECO:0000313|Proteomes:UP000217083};
RA Huang Z.;
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:OZM58654.1, ECO:0000313|Proteomes:UP000217083}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SA5d-4 {ECO:0000313|EMBL:OZM58654.1,
RC ECO:0000313|Proteomes:UP000217083};
RA Liu R., Dong C., Shao Z.;
RT "Bacillus patelloidae sp. nov., isolated from the intestinal tract of a
RT marine limpet.";
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: This protein is involved in the repair of mismatches in DNA.
CC It is possible that it carries out the mismatch recognition step. This
CC protein has a weak ATPase activity. {ECO:0000256|HAMAP-Rule:MF_00096}.
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutS family.
CC {ECO:0000256|ARBA:ARBA00006271, ECO:0000256|HAMAP-Rule:MF_00096,
CC ECO:0000256|RuleBase:RU003756}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OZM58654.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; NPIA01000001; OZM58654.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A263BY61; -.
DR Proteomes; UP000217083; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0006298; P:mismatch repair; IEA:UniProtKB-UniRule.
DR CDD; cd03284; ABC_MutS1; 1.
DR Gene3D; 1.10.1420.10; -; 2.
DR Gene3D; 3.40.1170.10; DNA repair protein MutS, domain I; 1.
DR Gene3D; 3.30.420.110; MutS, connector domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR HAMAP; MF_00096; MutS; 1.
DR InterPro; IPR005748; DNA_mismatch_repair_MutS.
DR InterPro; IPR007695; DNA_mismatch_repair_MutS-lik_N.
DR InterPro; IPR017261; DNA_mismatch_repair_MutS/MSH.
DR InterPro; IPR000432; DNA_mismatch_repair_MutS_C.
DR InterPro; IPR007861; DNA_mismatch_repair_MutS_clamp.
DR InterPro; IPR007696; DNA_mismatch_repair_MutS_core.
DR InterPro; IPR016151; DNA_mismatch_repair_MutS_N.
DR InterPro; IPR036187; DNA_mismatch_repair_MutS_sf.
DR InterPro; IPR007860; DNA_mmatch_repair_MutS_con_dom.
DR InterPro; IPR036678; MutS_con_dom_sf.
DR InterPro; IPR045076; MutS_family.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR01070; mutS1; 1.
DR PANTHER; PTHR11361:SF34; DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11361; DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER; 1.
DR Pfam; PF01624; MutS_I; 1.
DR Pfam; PF05188; MutS_II; 1.
DR Pfam; PF05192; MutS_III; 1.
DR Pfam; PF05190; MutS_IV; 1.
DR Pfam; PF00488; MutS_V; 1.
DR PIRSF; PIRSF037677; DNA_mis_repair_Msh6; 2.
DR SMART; SM00534; MUTSac; 1.
DR SMART; SM00533; MUTSd; 1.
DR SUPFAM; SSF55271; DNA repair protein MutS, domain I; 1.
DR SUPFAM; SSF53150; DNA repair protein MutS, domain II; 1.
DR SUPFAM; SSF48334; DNA repair protein MutS, domain III; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00486; DNA_MISMATCH_REPAIR_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|HAMAP-
KW Rule:MF_00096};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|HAMAP-
KW Rule:MF_00096}; Reference proteome {ECO:0000313|Proteomes:UP000217083}.
FT DOMAIN 678..694
FT /note="DNA mismatch repair proteins mutS family"
FT /evidence="ECO:0000259|PROSITE:PS00486"
FT BINDING 604..611
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00096"
SQ SEQUENCE 860 AA; 97965 MW; 6FD181E190411193 CRC64;
MSEYTPMIKQ YLAIKAQYKD AFLFFRLGDF YEMFFEDAVT ASQELEITLT SRDGGQIPMC
GVPHHSAEGY INRLIEKGYK VALCEQVEDP KHAKGVVKRE VVQLITPGTV MNGSIVSEKE
NNYLAAITCF SDGTFGLALC DLTTGENKVT LLQEGKDELI HELFSSGAKE VVVASNVDES
LLQAIQERLE VTVSREDESF IPDEFTTLVE NIEQPKLIES FARLLQYMIR TQKRSLDHLQ
PVFYFEVNEF MKIDMHSKRN LELVESNRNK SRKGSLLWLL DKTVTAMGGR MLKQWIERPL
ITKEKIETRQ QMVETFVQQF FERENLREQL KGVYDLERLA GRVAFGNVNA RDLIQLKKSL
QQVPEIISTL QQLDNPYSSE LAEKMDPCER LTAMLEKSIQ PSPPLSIKDG DIINDGYNEQ
LDRYRDATRN GKAWIAQLQQ QEREETGIKS LKIGYNKVFG YYIEVTKANL HLLPEGKYER
KQTLTNAERY ITPELKEKES LILDAEEKIV QLEYELFIAL REEVKTYIPV MQKLARQISE
IDCLQSFATI SENYHYVKPT FSENRNVLIK EGRHPVVEKM MNSQEYVAND VELNASRETL
LITGPNMSGK STYMRQVALT AIMAQIGCFI PADSAELPIF DKVFTRIGAA DDLAAGQSTF
MVEMLETKLA LAKATQNSLI LLDEIGRGTS TYDGMALAQA IIEYISEEIK AKTMFSTHYH
ELTDLEDELE ALHNVHVSAI EENGKVVFLH KVRDGRADES YGIHVAQLAE LPDKLIVRAR
EILAKLESGQ SKNKPTTSKV NQKTEEEQLS LFVAENNNVT PPIGSKEQKV LKQLQEMNML
EMTPLEAMNK LYDLQKKLKA
//
