ID   A0A263DLS2_9PSEU        Unreviewed;       314 AA.
AC   A0A263DLS2;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=Flap endonuclease {ECO:0000313|EMBL:OZM78537.1};
GN   ORFNames=CFP66_29865 {ECO:0000313|EMBL:OZM78537.1};
OS   Pseudonocardia sp. MH-G8.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Pseudonocardia.
OX   NCBI_TaxID=1854588 {ECO:0000313|EMBL:OZM78537.1, ECO:0000313|Proteomes:UP000216936};
RN   [1] {ECO:0000313|EMBL:OZM78537.1, ECO:0000313|Proteomes:UP000216936}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MH-G8 {ECO:0000313|EMBL:OZM78537.1,
RC   ECO:0000313|Proteomes:UP000216936};
RA   Wang J., Leiva S., Huang J., Huang Y.;
RT   "Non-contiguous finished genome sequence and description of Pseudonocardia
RT   marinum sp. nov., an obligate marine actinomycete from a macroalgal
RT   phycosphere.";
RL   Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OZM78537.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; NKYF01000017; OZM78537.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A263DLS2; -.
DR   OrthoDB; 9806424at2; -.
DR   Proteomes; UP000216936; Unassembled WGS sequence.
DR   GO; GO:0017108; F:5'-flap endonuclease activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0033567; P:DNA replication, Okazaki fragment processing; IEA:InterPro.
DR   CDD; cd09898; H3TH_53EXO; 1.
DR   CDD; cd09859; PIN_53EXO; 1.
DR   Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   InterPro; IPR020046; 5-3_exonucl_a-hlix_arch_N.
DR   InterPro; IPR002421; 5-3_exonuclease.
DR   InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR   InterPro; IPR020045; DNA_polI_H3TH.
DR   InterPro; IPR038969; FEN.
DR   InterPro; IPR008918; HhH2.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   PANTHER; PTHR42646:SF2; DNA-DIRECTED DNA POLYMERASE; 1.
DR   PANTHER; PTHR42646; FLAP ENDONUCLEASE XNI; 1.
DR   Pfam; PF01367; 5_3_exonuc; 1.
DR   Pfam; PF02739; 5_3_exonuc_N; 1.
DR   SMART; SM00475; 53EXOc; 1.
DR   SMART; SM00279; HhH2; 1.
DR   SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   SUPFAM; SSF88723; PIN domain-like; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Endonuclease {ECO:0000313|EMBL:OZM78537.1};
KW   Hydrolase {ECO:0000313|EMBL:OZM78537.1};
KW   Nuclease {ECO:0000313|EMBL:OZM78537.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000216936}.
FT   DOMAIN          1..281
FT                   /note="5'-3' exonuclease"
FT                   /evidence="ECO:0000259|SMART:SM00475"
SQ   SEQUENCE   314 AA;  33109 MW;  F1358B4DF6463912 CRC64;
     MLLDAASMYF RAFYGVPESI TAPDGTPVNA VRGFTDMVAR LITDRRPTRL VACLDLDWRP
     AFRVQALPSY KAHRVPGEPE VAPAGLPEEV PDLLAPQVPV LLEVLAAAGI ATGGAEGYEA
     DDVIGTLAAG ERTDPVLAVS GDRDLMQIVR DEPVPVRLLY VGRGLAKAEH LGPVEVAAKY
     GVPADRAGTA YAEMAMLRGD PSDGLPGVPG IGTKTAATLV GRFGSWDELR AAVIDKADTR
     LSPPVRVKLA AAAPYLAVVE PVVRVAVDAE VRLDRPDTLP AEPADLPRLA ALGERWGIGS
     SIERLCTAMA KNAS
//