ID   A0A263DMZ4_9PSEU        Unreviewed;       366 AA.
AC   A0A263DMZ4;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=Arsenical-resistance protein {ECO:0000313|EMBL:OZM79943.1};
GN   Name=arsB {ECO:0000313|EMBL:OZM79943.1};
GN   ORFNames=CFP66_23370 {ECO:0000313|EMBL:OZM79943.1};
OS   Pseudonocardia sp. MH-G8.
OC   Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
OC   Pseudonocardiaceae; Pseudonocardia.
OX   NCBI_TaxID=1854588 {ECO:0000313|EMBL:OZM79943.1, ECO:0000313|Proteomes:UP000216936};
RN   [1] {ECO:0000313|EMBL:OZM79943.1, ECO:0000313|Proteomes:UP000216936}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MH-G8 {ECO:0000313|EMBL:OZM79943.1,
RC   ECO:0000313|Proteomes:UP000216936};
RA   Wang J., Leiva S., Huang J., Huang Y.;
RT   "Non-contiguous finished genome sequence and description of Pseudonocardia
RT   marinum sp. nov., an obligate marine actinomycete from a macroalgal
RT   phycosphere.";
RL   Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651,
CC       ECO:0000256|PIRNR:PIRNR005508}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|PIRNR:PIRNR005508}.
CC       Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59)
CC       family. {ECO:0000256|ARBA:ARBA00010110, ECO:0000256|PIRNR:PIRNR005508}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OZM79943.1}.
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DR   EMBL; NKYF01000010; OZM79943.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A263DMZ4; -.
DR   OrthoDB; 3420410at2; -.
DR   Proteomes; UP000216936; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015297; F:antiporter activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0015103; F:inorganic anion transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1530.20; -; 1.
DR   InterPro; IPR004706; Arsenical-R_Acr3.
DR   InterPro; IPR002657; BilAc:Na_symport/Acr3.
DR   InterPro; IPR038770; Na+/solute_symporter_sf.
DR   NCBIfam; TIGR00832; acr3; 1.
DR   PANTHER; PTHR43057:SF1; ARSENICAL-RESISTANCE PROTEIN 3; 1.
DR   PANTHER; PTHR43057; ARSENITE EFFLUX TRANSPORTER; 1.
DR   Pfam; PF01758; SBF; 1.
DR   PIRSF; PIRSF005508; Acr3; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|PIRNR:PIRNR005508};
KW   Membrane {ECO:0000256|PIRNR:PIRNR005508, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000216936};
KW   Transmembrane {ECO:0000256|PIRNR:PIRNR005508, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|PIRNR:PIRNR005508,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|PIRNR:PIRNR005508}.
FT   TRANSMEM        21..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        50..72
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        93..112
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        118..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        149..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        190..210
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        231..249
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        269..288
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        295..317
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        323..343
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   366 AA;  39307 MW;  2D7188608B7BFE56 CRC64;
     MSTTPELEAP VAARLSTLDR FLPAWILAAM ALGLVAGRLV PGLGAALDTI VIQGISLPIA
     LGLLIMMYPV LAKVRYDRLD TVTGDRRLLV SSLVLNWVFG PALMFALAWL MLPDLPEYRT
     GLIIVGLARC IAMVIIWNDL ACGDREAAAV LVALNSVFQL IAFAALGWFY LDLLPGWLGL
     PQTALDVSPW EIALNVLIFL GIPLAAGYLT RRLGERAKGR EWYESRFLPR IGPFALYGLL
     FTIVILFALQ GDAILGQPLD VVRIALPLLA YFAIMWAGSY ALGCAIGLNY ERTTTLAFTA
     AGNNFELAIA VAIATFGVTS GQALAGVVGP LIEVPVLVAL VYVSLAARRR WRGATPTTAT
     PSAKES
//