ID A0A265Q5M6_9FIRM Unreviewed; 450 AA.
AC A0A265Q5M6;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=MATE family efflux transporter {ECO:0000313|EMBL:OZV11824.1};
GN ORFNames=CIW83_12295 {ECO:0000313|EMBL:OZV11824.1};
OS Tissierella sp. P1.
OC Bacteria; Bacillota; Tissierellia; Tissierellales; Tissierellaceae;
OC Tissierella.
OX NCBI_TaxID=1280483 {ECO:0000313|EMBL:OZV11824.1, ECO:0000313|Proteomes:UP000216906};
RN [1] {ECO:0000313|EMBL:OZV11824.1, ECO:0000313|Proteomes:UP000216906}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P1 {ECO:0000313|EMBL:OZV11824.1,
RC ECO:0000313|Proteomes:UP000216906};
RA Bukhtiyarova P.A., Antsiferov D.V., Avakyan M.R., Frank Y.A., Ikkert O.P.,
RA Pimenov N.V., Brasseur G., Tuovinen O.H., Karnachuk O.V.;
RT "Isolation and Characterization of an Anaerobic Sulfidogenic Tissierella
RT from Cu-bearing Coins.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OZV11824.1}.
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DR EMBL; NPMN01000016; OZV11824.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A265Q5M6; -.
DR OrthoDB; 9780160at2; -.
DR Proteomes; UP000216906; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR CDD; cd13134; MATE_like_8; 1.
DR InterPro; IPR002528; MATE_fam.
DR InterPro; IPR048279; MdtK-like.
DR InterPro; IPR047135; YsiQ.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR42925; MULTIDRUG AND TOXIN EFFLUX PROTEIN MATE FAMILY; 1.
DR PANTHER; PTHR42925:SF2; NA+ DRIVEN MULTIDRUG EFFLUX PUMP; 1.
DR Pfam; PF01554; MatE; 2.
DR PIRSF; PIRSF006603; DinF; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000216906};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 56..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..121
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 165..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..216
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 320..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 359..381
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 393..413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 450 AA; 49908 MW; 31882A82C0240B43 CRC64;
MKQFWKDKKF LKDMLVIAIP IALQNLITSS LNMVDTLMIS ELGKSSIAAV GLANQLFFFY
SLIIFGINSG SSIFISQFWG KNDTENIKRV LGLAVSLSAL SGLIFTMVAF FCPEIVMRFF
IKEEIVVRLG SDYLRIVSLS YIITGISFAF SIASRSIGQP KMPMIVSAIS FITNTIFNYL
LIFGHFGFPE LGVKGAAYGT LIARIVEISF ILYFVYTGIK PLAATLRELT DWTKEFVNRY
LKTTYPVIIN ETFWALGQVM YSAAYARMGA EATAAVQVAS TIQNIFFVMV RGLANACTVM
VGNKIGAGDE EEAYNYAIQF LTMSTIAGLA LGVILGLTPD LTLKLFRNLE LDVYNLSRKL
LMVAGIFYFI RTFNSTLIVG VLRGGGDTSF SMYLEMGAVW LIGVPLAFIG VLLLKLPVYI
VFILVSFEEI VKAVIGLPRV KSKKWIRNVT
//
