ID A0A267DHV5_9PLAT Unreviewed; 530 AA.
AC A0A267DHV5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE RecName: Full=Guanylate kinase/L-type calcium channel beta subunit domain-containing protein {ECO:0000259|SMART:SM00072};
GN ORFNames=BOX15_Mlig034250g1 {ECO:0000313|EMBL:PAA48795.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA48795.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA48795.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA48795.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA48795.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA48795.1}.
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DR EMBL; NIVC01004053; PAA48795.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267DHV5; -.
DR STRING; 282301.A0A267DHV5; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0005891; C:voltage-gated calcium channel complex; IEA:InterPro.
DR GO; GO:0005245; F:voltage-gated calcium channel activity; IEA:InterPro.
DR CDD; cd11863; SH3_CACNB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR008145; GK/Ca_channel_bsu.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR000584; VDCC_L_bsu.
DR PANTHER; PTHR11824:SF5; CA2+-CHANNEL-PROTEIN-BETA-SUBUNIT, ISOFORM L; 1.
DR PANTHER; PTHR11824; VOLTAGE-DEPENDENT CALCIUM CHANNEL BETA SUBUNIT; 1.
DR Pfam; PF00625; Guanylate_kin; 1.
DR PRINTS; PR01626; LCACHANNELB.
DR SMART; SM00072; GuKc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000215902}.
FT DOMAIN 232..413
FT /note="Guanylate kinase/L-type calcium channel beta
FT subunit"
FT /evidence="ECO:0000259|SMART:SM00072"
FT REGION 1..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 157..205
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 432..530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 25..55
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 157..182
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..471
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 487..506
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 530 AA; 58274 MW; 377A40E0B56FC5D8 CRC64;
MNANFGWQDN PYRGNLAAQP VGPANNYVQA DSNFSSQGSL IRQGSAESSY SGRSSAEPVL
DEDAKRERQR QAAEQLEKAK TKPVAFAVRT NIAYNGSSDA ESPVPGQAIT FDVKDFLHIK
EKFDSYWWIG RLVRENCDCQ FVPSPARLDC LRVQQRSGTS KSSGTAAGGL TAGSSSGTPP
VQSPLVDVAE ESDKADSDSL GRGATIGRSD AARKKAFFKK SDSSPPYEVV PSMRPVVLIG
PSLKGYEVTD MMQRAMFDFL KRRFEGRIII TQVSADISLA KRSVLNNPNR WALIERGSRA
SNIAEVQQEI ERIFELARTL QLVVLDCDTI NHPGQLAKTS LAPIVVYLKI NSLKVLQRLI
KSRGKSQTRS MTQQLSLAEK LQQCSADLYD VVLDENQLED ACEHLAEYLE AYWRATHPPS
MLSKAERLLG MSGQSTAGGH QHHQHMLHHQ HHQHHQQQQA AQPSNAASSA AGAAAAATGG
GLWSGDPEDY RSDRQLRVDR GGQQHPQQQR RRQLPQPPGN QPRPQGSIPI
//
