ID A0A267DLW9_9PLAT Unreviewed; 220 AA.
AC A0A267DLW9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Caspase family p20 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=BOX15_Mlig015048g3 {ECO:0000313|EMBL:PAA47793.1},
GN BOX15_Mlig033229g1 {ECO:0000313|EMBL:PAA87785.1}, BOX15_Mlig033229g2
GN {ECO:0000313|EMBL:PAA50298.1};
OS Macrostomum lignano.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA50298.1, ECO:0000313|Proteomes:UP000215902};
RN [1] {ECO:0000313|EMBL:PAA50298.1, ECO:0000313|Proteomes:UP000215902}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DV1 {ECO:0000313|EMBL:PAA50298.1};
RC TISSUE=Whole organism {ECO:0000313|EMBL:PAA50298.1};
RA Berezikov E.;
RT "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT model organism for stem cell research.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase C14A family.
CC {ECO:0000256|ARBA:ARBA00010134, ECO:0000256|RuleBase:RU003971}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAA50298.1}.
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DR EMBL; NIVC01004333; PAA47793.1; -; Genomic_DNA.
DR EMBL; NIVC01003677; PAA50298.1; -; Genomic_DNA.
DR EMBL; NIVC01000217; PAA87785.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A267DLW9; -.
DR STRING; 282301.A0A267DLW9; -.
DR Proteomes; UP000215902; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR Gene3D; 3.40.50.1460; -; 1.
DR InterPro; IPR029030; Caspase-like_dom_sf.
DR InterPro; IPR016129; Caspase_his_AS.
DR InterPro; IPR011600; Pept_C14_caspase.
DR InterPro; IPR002138; Pept_C14_p10.
DR InterPro; IPR001309; Pept_C14_p20.
DR InterPro; IPR015917; Pept_C14A.
DR PANTHER; PTHR22576:SF41; CASPASE 23-RELATED; 1.
DR PANTHER; PTHR22576; MUCOSA ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1/PARACASPASE; 1.
DR Pfam; PF00656; Peptidase_C14; 1.
DR PRINTS; PR00376; IL1BCENZYME.
DR SMART; SM00115; CASc; 1.
DR SUPFAM; SSF52129; Caspase-like; 1.
DR PROSITE; PS01121; CASPASE_HIS; 1.
DR PROSITE; PS50207; CASPASE_P10; 1.
DR PROSITE; PS50208; CASPASE_P20; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000215902}.
FT DOMAIN 1..89
FT /note="Caspase family p20"
FT /evidence="ECO:0000259|PROSITE:PS50208"
FT DOMAIN 104..182
FT /note="Caspase family p10"
FT /evidence="ECO:0000259|PROSITE:PS50207"
FT REGION 184..203
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 220 AA; 24922 MW; 9A6323DE6A5BA12F CRC64;
MADTLLRLGY SVSIRSNLTK VEIESELDMF CSDARHGSSV VVAFMSHGCL GEVVGFDGES
AKESKILKRI SKGKRTSRKQ QLVIFENCRD PGRWPKSELA FFPDMIVAHS TSPDESSYRM
TDRGSRFIQC LCTVLDLFAD KCDIASMVPI VNYVVQNATF NLGISQLPWW SVQTSKKFWI
RVNEPPQSSR ESRQQANSAR NQTTNDCRVQ VTELLQKMRL
//
