ID   A0A267DQL1_9PLAT        Unreviewed;      1015 AA.
AC   A0A267DQL1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   RecName: Full=PKD/Chitinase domain-containing protein {ECO:0000259|SMART:SM00089};
DE   Flags: Fragment;
GN   ORFNames=BOX15_Mlig025460g1 {ECO:0000313|EMBL:PAA50822.1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA50822.1, ECO:0000313|Proteomes:UP000215902};
RN   [1] {ECO:0000313|EMBL:PAA50822.1, ECO:0000313|Proteomes:UP000215902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DV1 {ECO:0000313|EMBL:PAA50822.1};
RC   TISSUE=Whole organism {ECO:0000313|EMBL:PAA50822.1};
RA   Berezikov E.;
RT   "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT   model organism for stem cell research.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAA50822.1}.
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DR   EMBL; NIVC01003555; PAA50822.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A267DQL1; -.
DR   STRING; 282301.A0A267DQL1; -.
DR   Proteomes; UP000215902; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd00146; PKD; 2.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR029865; KIAA0319-like.
DR   InterPro; IPR022409; PKD/Chitinase_dom.
DR   InterPro; IPR002859; PKD/REJ-like.
DR   InterPro; IPR035986; PKD_dom_sf.
DR   PANTHER; PTHR46182; FI19480P1; 1.
DR   PANTHER; PTHR46182:SF2; FI19480P1; 1.
DR   Pfam; PF02010; REJ; 1.
DR   SMART; SM00089; PKD; 4.
DR   SUPFAM; SSF49299; PKD domain; 4.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        875..897
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          351..443
FT                   /note="PKD/Chitinase"
FT                   /evidence="ECO:0000259|SMART:SM00089"
FT   DOMAIN          451..538
FT                   /note="PKD/Chitinase"
FT                   /evidence="ECO:0000259|SMART:SM00089"
FT   DOMAIN          546..633
FT                   /note="PKD/Chitinase"
FT                   /evidence="ECO:0000259|SMART:SM00089"
FT   DOMAIN          647..733
FT                   /note="PKD/Chitinase"
FT                   /evidence="ECO:0000259|SMART:SM00089"
FT   REGION          972..1015
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1000..1015
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:PAA50822.1"
SQ   SEQUENCE   1015 AA;  106693 MW;  16DD23BEF8BE42D3 CRC64;
     SRQIDCPMPL LSNRPLLALT VALATATIIV VPMATAVEVP ANSAAGIAGD GVDACALPKP
     QLLRLDGLPR AAPRSGKLAG VYKKFANISD LPGCASLCCA NPACHSALLY KSECFIVSCR
     SALACQPRRR KSADADKAVY LPLRSVCAAG SDSACGDGHY CMSSACQAKK SCSMSTLGDC
     GPGEECNFGA SDSGSGSEGF CECRSGFVRR SSSGCQPAPL VVTTAAAATT AAPTATAVTT
     APSKREQLIV SAGSNRTIEL PLNSIELHAS IIPEPTGAAA KRLAYSWKVI SGPRKGQFQN
     RNTASLKLSE LVEGKYVLQV DVTDNTDSNR VGKAVVMVTV KPAKHKSKPP KAVIKPASLS
     IQLPNNAILD GSGSVDGDQK IESYHWQVVD GPLTAQDLHS VSQDQQILQL NNLKAGFYVI
     RLTVQDAKGL SDSATANITV IPEPDDKPKA SAGQSSVIYL PQNNITLYGN ASTDDHGIVS
     YMWRQKGGSH LSADMQGVHT PVLHLSGLVE GDYAFELTVT DARGQTDSAT VNVLVKRRPK
     NALPVVTLLP PELTVELPLT RLVLNASAVD DTGVKSWRWT LLTGPGSAKL ANATQPSVTL
     TNLQAGVYKL RAEAVDLDGG VGSAVVTVTV KPGPNQAPKA DAGGDRVVDM DGTGATLVAL
     DASKSWDDKG IVEYKWTRQD VSLAVGQVLN GSDASPRLLL LGLLPGRYSF RLTVKDSEGA
     TGTADAAILV RPWPHAASVA SLELRADPSA LRQSDLSNLM SQMQLTLRGP HPGCNLRLLG
     LRPRQASIVM RLSAGFANGT YLPGPRLAAV LKRRLPATLL EFPVLELHTE VCQLGCSDRG
     YCDNSTRQCV CASFWMENPL RVRFGDGESN CDWSVVYVSL GVTISLLGFC AAVWLLYCCL
     RYRRASAAAA AAHLRTGSGS KVRRLRKAAA MMAGGGGSRD KVFYAPLNNG NESGGRMSFS
     LSSDEEDTVY SRRVASDPSL GGGSGGAGDG GAKADHNSNR IPMASLSNGS VKSDK
//