ID   A0A267DWA3_9PLAT        Unreviewed;       678 AA.
AC   A0A267DWA3;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=Methyltransferase domain-containing protein {ECO:0000259|Pfam:PF13649};
DE   Flags: Fragment;
GN   ORFNames=BOX15_Mlig003755g4 {ECO:0000313|EMBL:PAA53601.1};
OS   Macrostomum lignano.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes;
OC   Rhabditophora; Macrostomorpha; Macrostomida; Macrostomidae; Macrostomum.
OX   NCBI_TaxID=282301 {ECO:0000313|EMBL:PAA53601.1, ECO:0000313|Proteomes:UP000215902};
RN   [1] {ECO:0000313|EMBL:PAA53601.1, ECO:0000313|Proteomes:UP000215902}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DV1 {ECO:0000313|EMBL:PAA53601.1};
RC   TISSUE=Whole organism {ECO:0000313|EMBL:PAA53601.1};
RA   Berezikov E.;
RT   "A platform for efficient transgenesis in Macrostomum lignano, a flatworm
RT   model organism for stem cell research.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAA53601.1}.
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DR   EMBL; NIVC01003057; PAA53601.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A267DWA3; -.
DR   STRING; 282301.A0A267DWA3; -.
DR   Proteomes; UP000215902; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR041698; Methyltransf_25.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR12176:SF78; EEF1A LYSINE AND N-TERMINAL METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR12176; SAM-DEPENDENT METHYLTRANSFERASE SUPERFAMILY PROTEIN; 1.
DR   Pfam; PF13649; Methyltransf_25; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215902};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          65..167
FT                   /note="Methyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF13649"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:PAA53601.1"
SQ   SEQUENCE   678 AA;  74380 MW;  8EB796D354F840E8 CRC64;
     NVAPLKVRKT TMSFKLLPKS TEEFSDTKFW EGFFKTRGSK AFEWYGEYQD MVELWAQYVK
     TGDRVLNIGC GNSNLGAELH DYQNCEVLCI DTSSTVVQQM SRKHSKRPRL SYRVMDAANL
     EGLNDGSFAC AVDKGTLDAL MSAADSSIQA VVDGMLAEAH RVLRVGGRHL IVSLCQKQVV
     DKLVQHISLR PWIARVHQVA STSASDSSGF PLPVFFIALT KLRPEAAATA TAVSSIVQVQ
     DAYSTGPPER LDSVASLTDW IRQVQLTAYS LSRSSGMEIN STDASGDADS QCRVTQFSYS
     CGRTGLPTFT CHLLTHVATS SRRRTGYAVF IEPLGSSACR LSPSDRRDLL ESQSNLRRLL
     FVKLHPWLHY QSDTALQASL SRLVMAFAPK PGMPESQVPF LSTGRLAYPY QSVATRIGYI
     VEQSEDDSQT KELRLLRPES DLSPLLCCAN AALVKSVSST VCSDIVAEAG NSPLGRLLDQ
     LIGISSDTNP CALINWPCNL DWLLTYKHRQ PERPPPKLYV SASSPAVSLL AEYFNLTWTA
     TKQPFALDSR HRLVALFPPA DSLASYAAAV TPESIASLAS AIESDGCLLL ATRLFDSKQQ
     VSNINARAVD SLRQCSQFVD VICATFSDED IDAKQVEIDE SAEHRCRWWI ACALMSIGSK
     SLIEDFLAGL PGCQLIEA
//